Both prescription and non-prescription drugs can affect your driving. It is important to read the labels before starting any new medication. You can also talk to your doctor or pharmacist about side effects.
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Sure they can. Some will do it if someone overdoses on them, or mixes medications against doctor's recommendations. Of if a person has a stronger-than-average reaction to them. Some will "always" do it, and will have a warning label on them. And the patient will be advised about their effect.
Some can, some can't. It depends on the drug. This will be indicated on the label, but consult the pharmacist for details.