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Can indirect bilirubin be more than total bilirubin?
yes
What circumstance leads to higher than normal levels of bilirubin in newborn babies?
Before birth, an infant gets rid of bilirubin through the mother's blood and liver systems. After birth, the baby's liver has to take over processing bilirubin on its own.
Is Bilirubin being at 1.7mg in human blood fatal or serious?
A bilirubin level of 1.7mg/dL in human blood is slightly elevated but not typically considered fatal or serious on its own. It may indicate liver or bile duct issues that need monitoring and further investigation by a healthcare provider. Treatment would depend on the underlying cause of the elevated bilirubin levels.
What is the significance of 1.5mg bilirubin lab results?
Depends on if you're talking about a newborn or an adult. Newborns have a higher normal range than adults. For instance, in Colorado we establish a certain range from the normal population that may differ from the rest of the nation. Adults can run up to 1.0 mg/dl. Anything from 0 to 1.0 mg/dl is considered normal. 1.5 mg/dl is high and may require additional lab work or other studies to determine the cause of the high bilirubin. The physician may request that the lab break the bilirubin test down into direct vs. indirect bilirubin. Direct bilirubin is a measure of how much of the bilirubin is not soluble and therefore not excreted in the urine. Sunlight can actually "conjugate the bilirubin" to make it more soluble in the urine and therefore excretable in the urine. This is why they put babies with "jaundice" or high bilirubin under bili lights. Bili lights will help turn the unconjugated biliruben into soluble biliruben which can then be excreted in the urine. Increased bilirubin in adults can point to several disease states like cirrhosis of the live due to viral hepatitis, alcoholism or other factors. Very high bilirubin levels in infants can cause brain damage, so treatment like exchange transfusion may be in order.
Bilirubin - blood?
DefinitionBilirubin is a yellowish pigment found in bile, a fluid produced by the liver.This article discusses the laboratory test done to measure bilirubin in the blood. Total and direct bilirubin are usually measured to screen for or to monitor liver or gallbladder problems. Large amounts of bilirubin in the body can lead to jaundice.A test may also be done to measure bilirubin in a urine sample. For information on that test, see: Bilirubin - urine.Alternative NamesTotal bilirubin - blood; Unconjugated bilirubin - blood; Indirect bilirubin - blood; Conjugated bilirubin - blood; Direct bilirubin - bloodHow the test is performedA blood sample is needed. For information on how this is done, see: Venipuncture.The laboratory specialist spins the blood in a machine called a centrifuge, which separates the liquid part of the blood (serum) from the cells. The bilirubin test is done on the serum.How to prepare for the testYou should not eat or drink for at least 4 hours before the test. Your health care provider may instruct you to stop taking drugs that affect the test.Drugs that can increase bilirubin measurements include allopurinol, anabolic steroids, some antibiotics, antimalaria medications, azathioprine, chlorpropamide, cholinergics, codeine, diuretics, epinephrine, meperidine, methotrexate, methyldopa, MAO inhibitors, morphine, nicotinic acid, birth control pills, phenothiazines, quinidine, rifampin, steroids, sulfonamides, and theophylline.Drugs that can decrease bilirubin measurements include barbiturates, caffeine, penicillin, and high-dose salicylates such as aspirin.Why the test is performedThis test is useful in determining if a patient has liver disease or a blocked bile duct.Bilirubin metabolism begins with the breakdown of red blood cells in many parts of the body. Red blood cells contain hemoglobin, which is broken down to heme and globin. Heme is converted to bilirubin, which is then carried by albumin in the blood to the liver.In the liver, most of the bilirubin is chemically attached to another molecule before it is released in the bile. This "conjugated" (attached) bilirubin is called direct bilirubin; unconjugated bilirubin is called indirect bilirubin. Total serum bilirubin equals direct bilirubin plus indirect bilirubin.Conjugated bilirubin is released into the bile by the liver and stored in the gallbladder, or transferred directly to the small intestines. Bilirubin is further broken down by bacteria in the intestines, and those breakdown products contribute to the color of the feces. A small percentage of these breakdown compounds are taken in again by the body, and eventually appear in the urine.Normal ValuesDirect bilirubin: 0 to 0.3 mg/dLTotal bilirubin: 0.3 to 1.9 mg/dLNote: mg/dL = milligrams per deciliterNormal values may vary slightly from laboratory to laboratory.What abnormal results meanJaundice is a yellowing of the skin and the white part of the eye, which occurs when bilirubin builds up in the blood at a level greater than approximately 2.5 mg/dL. Jaundice occurs because red blood cells are being broken down too fast for the liver to process. This might happen due to liver disease or bile duct blockage.If the bile ducts are blocked, direct bilirubin will build up, escape from the liver, and end up in the blood. If the levels are high enough, some of it will appear in the urine. Only direct bilirubin appears in the urine. Increased direct bilirubin usually means that the biliary (liver secretion) ducts are obstructed.Increased indirect or total bilirubin may be a sign of:Crigler-Najjar syndromeErythroblastosis fetalisGilbert's diseaseHealing of a large hematoma (bruise or bleeding under the skin)Hemolytic anemiaHemolytic disease of the newbornHepatitisPhysiological jaundice (normal in newborns)Sickle cell anemiaTransfusion reactionPernicious anemiaIncreased direct bilirubin may indicate:Bile duct obstructionCirrhosisDubin-Johnson syndrome (very rare)HepatitisIntrahepatic cholestasis (buildup of bile in the liver) due to any causeAdditional conditions under which the test may be performed:Biliary strictureCholangiocarcinomaCholangitisCholedocholithiasisHemolytic anemia due to G6PD deficiencyHepatic encephalopathyIdiopathic aplastic anemiaIdiopathic autoimmune hemolytic anemiaImmune hemolytic anemia (including drug-induced immune hemolytic anemia)Secondary aplastic anemiaThrombotic thrombocytopenic purpuraWilson's diseaseSpecial considerationsFactors that interfere with bilirubin testing are:Hemolysis (breakdown) of blood will falsely increase bilirubin levelsLipids in the blood will falsely decrease bilirubin levelsBilirubin is light-sensitive; it breaks down in lightReferencesBerk PD, Korenblat KM. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 150.
What is the excretory product other than urea formed by liver?
In addition to urea, the liver produces bilirubin as a result of the recycling of red blood cells. The bilirubin is excreted through bile.
What is the discoloration of the skin caused by greater than normal amounts of bilirubin called?
"Jaundice" is.
Why would newborn babies be exposed to sunshine?
0-6 months: Infants under 6 months of age should be kept out of the sun. Their skin is too sensitive for sunscreen. An infant's skin possesses little melanin, the pigment that gives colour to skin, hair and eyes and provides some sun protection. Therefore, babies are especially susceptible to the sun's damaging effects.So it isn't really safe but, only some people do it but, there isn't a clear reason why.HERE IS ANOTHER ANSWER:A common condition for newborns is jaundice (yellowing of the skin and sclera of the eyes). Jaundice occurs when the baby produces more bilirubin than the liver can process. Bilirubin is a by product of normal breakdown of red blood cells. The three most common reasons for excess bilirubin are excess production of bilirubin due to the baby's normally higher than adult turn over of red blood cells, immature liver that cannot keep up with normal bilirubin production, or reabsorption of bilirubin by the intestines. the most common treatment of jaundice is phototherapy, the exposure of the child to special lighting that helps alter the by product to make it easier for the child's liver to process it. Some pediatricians may suggest the exposure of the child to brief periods of natural daylight if bilirubin levels are below 15-25mg.
What disorder occurs with jaundice?
The hemoglobin that is released when the cells die is turned into bilirubin. If for any reason the RBCs die at a faster rate than usual, bilirubin can accumulate in the blood and cause jaundice.
What does a country experience when the total value of exports is higher than the total value of imports?
they will fell differentthey will
What is a normal bilirubin level for a 50 yr old male?
normal value of bilirubin in blood is (0.5 - 1.5 mg/dl)refrence book:-Essential of madical physiology (5th edition) Jaypee page number 57.table 7-1.my name is ZULCAIFfrom hajveri university
What was the difference between the thermometer readings in the drawer and in direct sunlight?
The thermometer readings in the drawer were typically lower than in direct sunlight. This is because objects in the drawer are shielded from direct heat and radiation from the sun, resulting in a cooler temperature reading.
