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Generally Fluoxetine (US: Prozac) does not cause significant weight gain, but it has stronger sexual side effects. Also Escitalopram (US: Lexapro, EU: Cipralex) should not cause much weight gain.

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Q: What ssri does not make gain weight?
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Are there any SSRI that won't make you gain weight?

None for sure, but chances are Proxac (fluoxamine) will cause less if not at all. It has increased sexual side effects however.


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I would pick Prozac (fluoxetine), but that's not guaranteed. It has increased sexual side effects though. If you are really sensitive to weight gain, you may consider drugs of other classes. Wellbutrin doesn't cause weight gain for example, and may even improve sex. But I think it's not as strong as the SSRIs.


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