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It depends on the particular drug and what class of drug it belongs to. But for some of the most popular drugs it's generally the following;

- Amphetamines (psychological addiction, psychosis, irritability, fatigue, weight loss)

- Alcohol (physical and psychological addiction, brain damage, liver damage, cancer of the mouth, throat, esophagus and stomach, early onset alzheimers, parkinsons disease, korsakoff's syndrome, coma, death)

- Barbiturates (physical and psychological addiction, coma, death)

- Cannabis (clouded thinking, forgetfulness, when smoked along with tobacco reduced stamina, weight gain)

- Cocaine (psychological addiction, psychosis, anxiety, fatigue, weight loss, erosion of the nasal passages when snorted, lung problems when smoked)

- Ecstacy (psychological addiction, psychosis, depression, fatigue, weight loss)

- Ketamine (psychological addiction, psychosis, depression, fatigue

- LSD (psychosis in people who have a tendency to it)

- Magic mushrooms (psychosis in people who have a tendency to it)

- Opiates (physical and psychological addiction, constipation)

- PCP (psychosis)

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