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Generally doctors avoid SSRI and TCA combinations. Safer approaches are tried first, as switching to different agents, increasing dosages, SNRIs (Effexor and Cymbalta), combinations of SSRI and Wellbutrin, Remeron or buspirone (Buspar) or augmentation of the SSRI with modafinil (US: Provigil).

Well, if these didn't help you, you can try SSRI + TCA but expect some side effects that may be irritating. Most common from this combination should be dry mouth, constipation, weight gain, and of course sexual side effects.

If you have especially high anxiety, your doctor most certainly will prefer the use of SSRI + TCA from some of the above solutions.

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Q: Can you take a ssri and tricyclic together?
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Tricyclic antidepressants should not be given together with?

Tricyclic are a family of antidepressants that were given to people before the SSRI. Often psychiatrists prescribe a tricyclic and a newer anti-depressant usually a selective serotonin Inhibitor or a serotonin Norefenefphan selective inhibitor. Your doctor can usual decide what is safe


Is Zoloft a tricyclic antidepressant?

No, Zoloft is a selective serotonin reuptake inhibitor or SSRI.


Can you take Prozac Cymbalta and mirtazapine together?

yes , they can be taken together. Some studies show combining mirtazapine with ssri's make them more effective.


Can Effexor and amyltriptyline be taken together?

I do not recommend taking one of the older tricyclics along with an SSRI. Amitryptyline is extremely drying and sedating. If you are over 60 you should never take a tricyclic antidepressant.Taking two medicines which have sedating effects could make you pass out or become confused. The drying effects of amitryptiline can result in dizziness, disorientation, difficulty urinating, and severe headache.


Can you take Paxil and Celexa together?

You can but you risk developing "serotonin syndrome" which can be fatal. A better choice is to keep trying ONE antidepressent until you find one that works best. I find that taking paxil and clonopin works best for me. Generally, if an SSRI doesnt make you feel a lot better, the older tricyclic antidepressents (i.e. Elavil) will. (You really need to take a med for a whole month before deciding on it.)


Can you take Advil with Cymbalta?

Not a good idea. SSRI drugs combined with NSAID's cause increased bleeding. If you take both these med's you risk a GI or stomach bleed. Ask your doctor for stomach protection if you want to take these two together.


Can you take lamictal and Paxil together?

Yes. Lamictal is a mood stabilizer and paxil is an ssri (anti-depressant). Lamactil is often prescribed with SSRI's to "boost" the effect and/or work on areas that the SSRI does not tap. Obviously, an MD/Psych is the best person to talk to about drug interactions, not the internet.


Should you take Zoloft and Prozac together?

because they are both SSRI's, the two combined, especially at high doses could result in serotonin syndrome.


The three types of drugs used to treat depression?

The three types of drugs used to treat clinical depression is • MAOI's • SSRI's • Tricyclic Componds by:damien ward


Can you take antidepressants and tramadol together?

No, antidepressants can interact poorly with the pain reliever tramadol.


What are the main groups of depressants?

This is a great question. The history of antidepressants is diverse and even controversial. These drugs have had both positive and negative reviews and support over the years. The most contemporary and popular group of antidepressants are known as SSRI's (Selective Serotonin Reuptake Inhibitors).These medications include Paxil, Prozac, Cymbalta, or Celexa. They are referred to by mental health professionals as new generation antidepressants. SSRI's tend to have fewer side effects and take effect about 4-6 weeks after the first administration.The second and less popular class of drugs are known as Tricyclic Antidepressants. These medications are the oldest antidepressants available and often include the most and worst side effects such as dry mouth, headaches, dizziness, heart palputations, etc. Drugs under this category include Imiprimine or Amitryptaline.The final category of antidepressants include what are known as MAOI's (Monoamine Oxidase Inhibitors). These drugs can include a host of side effects and requires a very structured diet. Individuals who take MAOI's cannot have dairy (cheese, eggs) or certain wine products in their diet. Most psychiatrists adjust the diet of their patients and monitor blood pressure, etc. MAOI's inhibit the monoamine oxidase chemical in the brain. To learn more about MAOI's, visit the Mayoclinic online.MAOI's are the first antidepressant medications to be developed, followed by Tricyclic antidepressants, and then SSRI's. Most psychiatrists today will begin a patient on an SSRI. If SSRI's do not prove to be effective, Tricyclic antidepressants may be tried before MAOI's are implemented.


What are the three main groups of depressants?

This is a great question. The history of antidepressants is diverse and even controversial. These drugs have had both positive and negative reviews and support over the years. The most contemporary and popular group of antidepressants are known as SSRI's (Selective Serotonin Reuptake Inhibitors).These medications include Paxil, Prozac, Cymbalta, or Celexa. They are referred to by mental health professionals as new generation antidepressants. SSRI's tend to have fewer side effects and take effect about 4-6 weeks after the first administration.The second and less popular class of drugs are known as Tricyclic Antidepressants. These medications are the oldest antidepressants available and often include the most and worst side effects such as dry mouth, headaches, dizziness, heart palputations, etc. Drugs under this category include Imiprimine or Amitryptaline.The final category of antidepressants include what are known as MAOI's (Monoamine Oxidase Inhibitors). These drugs can include a host of side effects and requires a very structured diet. Individuals who take MAOI's cannot have dairy (cheese, eggs) or certain wine products in their diet. Most psychiatrists adjust the diet of their patients and monitor blood pressure, etc. MAOI's inhibit the monoamine oxidase chemical in the brain. To learn more about MAOI's, visit the Mayoclinic online.MAOI's are the first antidepressant medications to be developed, followed by Tricyclic antidepressants, and then SSRI's. Most psychiatrists today will begin a patient on an SSRI. If SSRI's do not prove to be effective, Tricyclic antidepressants may be tried before MAOI's are implemented.