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This is a great question. The history of antidepressants is diverse and even controversial. These drugs have had both positive and negative reviews and support over the years. The most contemporary and popular group of antidepressants are known as SSRI's (Selective Serotonin Reuptake Inhibitors).These medications include Paxil, Prozac, Cymbalta, or Celexa. They are referred to by mental health professionals as new generation antidepressants. SSRI's tend to have fewer side effects and take effect about 4-6 weeks after the first administration.

The second and less popular class of drugs are known as Tricyclic Antidepressants. These medications are the oldest antidepressants available and often include the most and worst side effects such as dry mouth, headaches, dizziness, heart palputations, etc. Drugs under this category include Imiprimine or Amitryptaline.

The final category of antidepressants include what are known as MAOI's (Monoamine Oxidase Inhibitors). These drugs can include a host of side effects and requires a very structured diet. Individuals who take MAOI's cannot have dairy (cheese, eggs) or certain wine products in their diet. Most psychiatrists adjust the diet of their patients and monitor blood pressure, etc. MAOI's inhibit the monoamine oxidase chemical in the brain. To learn more about MAOI's, visit the Mayoclinic online.

MAOI's are the first antidepressant medications to be developed, followed by Tricyclic antidepressants, and then SSRI's. Most psychiatrists today will begin a patient on an SSRI. If SSRI's do not prove to be effective, Tricyclic antidepressants may be tried before MAOI's are implemented.

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Q: What are the three main groups of depressants?
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