you have to defeat team rocket at their secret base at the game corner and the boss drops it after you defeat him
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saffron city
That building is in saffron city.
You need to get the Silph Scope.
It is located underneath the game corner in celadon city.
The ghosts can't be fought in their current forms. To beat them you have to see them and you can when you get a Silph Scope. You get the Silph Scope in Celadon City somewhere (No spoilers unless u want them)