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Not really, but dish detergent and glass cleaner are good for getting smudges and dust off. you should try that and see if it works.
Yes, you can buff the surface of a disc with toothpaste to remove, or lessen, scratches.
Try wiping the disc with a towel or tissue to rub off any dust. There are probably scratches on it. If that doesn't work, your game may have too many scratches.
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If the disc has scratches that make it not work, try using a pencil eraser and rub from the center to the edge. It rubs off a small layer that rubs away the scratches. Hope this helps!