E4 is classical if you dont watch anything on it then please try examples:My name is Earl, Friends, The big bang theory, Scrubs, One tree hill and the rest.
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To re battle red u must defeat the e4. After u beat the e4 red will reappear. do this as much as pleased
In Viridian Forest, or purchased at the second game corner. Only available after you beat the E4
I think Lucario.
You need to have defeated all the gyms as well as all the E4 before they are released onto the map.
Not really. You can still get Oak's Letter without it, but to get TO route 224, you need to beat the E4 and have the National dex.