Yes, you can attack the Dagannoth Mother with Ancient Magicks, but you need to use the correct spell type depending on her color phase. The Dagannoth Mother, encountered in the "Horror from the Deep" quest, changes her weakness based on her color:
White: Air spells (Ancient Magicks: Smoke spells)
Blue: Water spells (Ancient Magicks: Ice spells)
Orange: Earth spells (Ancient Magicks: Blood spells)
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There are two dagannoth mothers, from different quests. They will change colors, indicating specific weaknesses. You need elementary spells (water, air, earth fire) part of the time; if you don't have those, you have to wait until she changes to green (allowing ranged attacks) or orange (allowing melee attacks), so you'll be at a significant disadvantage if you don't use the normal spellbook. I believe that if you don't have a specific spell for the second dagannoth mother, her color may remain stuck at that particular weakness, so you won't be able to defeat her at all.
you can get it when you get the ancient mother carving on nineball island.it is located in the artic ocean on C3 by the ice mosiac
The WHITE mother?? you have to complete all your other missions first then she is at the coordinate C2
You have to have access to lavender town and travel to the top of the ghost tower. There, defeat cubones mother and the team rocket guards on top. Then an old man will take you to his house. talk to him and he will give you a blue flute. approach snorlax and press A and the flute will wake him up. he does attack
Its called the mother or a Lioness or whatever the species is
Each one us have a mother.