No. None of the instruments in any RockBand/Guitar Hero are cross platform compatible.
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If you mean is the original Xbox version cross-compatible with 360, then yes, it is.
Yes, on Xbox 360 all Guitar Hero world tour, Rockband, guitar hero 3 games are definitely cross compatible with instruments (obviously not with using the durms on guitar hero 3) and more then likely guitar hero 2.
Short answer, no. Some MMOs do use cross platform multi-player but if you are playing your basic Call of Duty than probably not.
People ON computers: Only if you are also on one. You don't game Cross-platform, usually. Computers, meaning AI's: Only for Firefight and the Campaign.
You will be riding a dinosaur when you find platform made out of five blocks above you. Get on top of this platform and jump up while standing on the middle block to reveal an invisible block that sprouts a Vine from the top. Climb the Vine up and enter the pipe. From here you'll need to bounce off the backs of the Scuttlebugs to cross the gap and reach the Alternate Flagpole Exit.