It is assumed she died. Cause not given. Maybe she died in childbirth, which is was a rural health problem more than an Urban one. Somehow it never entered into the plots., No pictures, etc For some reason death in the family ( always off screen)- was a more acceptable plot device than divorce or separation.
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Griffith was married three times: Barbara Giffith, Solica Casuto and Cindi Knight.
I don't think it was ever brought up, but at the beginning Andy talks of losing his wife (Opie's mom), which why Aunt Bea lives with them.
"The Andy Griffith Show" was a spin-off of "The Danny Thomas Show". In the Danny Thomas episode, Francis Bavier played a completely different character. When "The Andy Griffith Show" debuted, the first episode had Aunt Bea coming to live with Andy and Opie.
Wally's Filling Station is first mentioned in 'Man In A Hurry' also GoMer Pyle's first appearance.
Because Andy Griffith was the name of the actor who played Andy Taylor, hence the show was named after the actor, not the character.
andy griffith