Sakura asks Tsunade to train her in episode 141.
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Sakura had a desire to become stronger, as she was tired of relying on Naruto. Tsunade agreed to train her.
Tsunade because sakura is still in training but there are hints that say that once shes older she will be the new tsunade if not stronger
When Sakura realises that she is too weak to help other people, she decides to become a medical ninja and learn medical secrets from Tsunade. She learned how to heal people and also she now has great strength in her body just like Tsunade
Sakura and Ino was (in part1) about ecual in strength, but in Shippuden, Sakura is stronger than Ino. Ino's total stat is 21 and Sakura's stat is 26. Sakura gained enough strength and beauty thanks to Tsunade. Jiraiya said that Tsunade did a good job in making a younger Tsunade and Kakashi even said Sakura can surpass tsunade.
Ino and Sakura fought in the Chunin Exams , it was mentioned that their strength is equal. However, even though Sakura trained with Lady Tsunade , they both are still equal in strength. During the time-skip Sakura got stronger thanks to Tsunade and Sakura gained enough beauty too. Some say she is younger version of Tsunade or someone who could surpass Tsunade. And for Ino she improved a bit but i say Sakura is stronger.