The only reason Sasuke killed Itachi was becasue Itchi killed nearly everyone in the Uchiha Clan. So he had to get his revenge. Kabuto really didn't have mauch of a part in that except for munipulating him into thinking he would help him get stronger to fight Itachi
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Sasuke kills orochimaru then uses his body to take power from him and then kabuto uses the rest and later kills deidaara and itachi plus da only reason orochimaru wantedsasuke woz 2 tke da sharingan off him :P
Itachi at 13 years old submitted to a life sentence because of his duty as a shinobi. His dreams of creating a better world and for world peace by becoming a Homage was literally thrown out of the window. His remaining hope for he future was for his younger brother was to avenge their clan and freeing Itachi from his hell. Sasuke on the other hand, never investigated or found out the real reason why Itachi did what he did. Obito has to spoon-fed it to him, and then he went to go against his elder brother's wishes and lashed out, once again, and killed the man (the complete ahole elder, Danzo). I tachi could have killed Danzo if he wanted to, but he did not. That was how truly honourable this shinobi was compared to Sasuke. So the answer to your question: ITACHI.
ok after sasuke kills itachi he passes out. and then madara uchiha takes sasuke to a hidden location. its almost like a cave. and during the time of sasuke healing, madara tells sasuke the truth about itachi. he tells sasuke why itachi did all the things he did. and i have seen other questions asking " is itachi a good guy " and the answer to that is yes. you see itachi killed his clan on orders of the elders of the leaf and danzo because the uchiha clan were planning to attack the hidden leaf village. and itachi was a double spy he loved the hidden leaf village and he loved his clan. but he couldn't let all of the innocent people of the hidden leaf village die by the hand of his clan. so the elders and danzo sends him to kill the entire clan. but itachi couldn't do it alone. he had the help of the famous uchiha madara. also itachi cared and loved his brother so much that he couldn't bring himself to kill him. so in the end itachi leaves the clans place and goes to see the hokage. he tells the hokage that don't tell sasuke the truth and as a last request itachi asks that sasuke is looked out for and that nothing happens to him. and then in the end when itachi and sasuke fight. itachi did and said everything as a cover up. and itachi let himself be killed by his younger brother sasuke so that he could give sasuke all his eye techniques and give sasuke that mangekyou sharingan. ( it is unclear weather sasukes sharingan is eternal or not ) so then madara tells sasuke all of this and after a long time of thinking sasuke excepts the truth and falls into a deep hatred for the hidden leaf village for making his brother do such a horrible thing. and now sasuke wants to destroy the hiddden leaf village. and his group hawk has joined akutski and madara gives sasuke itachi's eyes so while sasuke is healing from the procedure madara & kabuto created the next ninja war & i believe that is where naruto & sasuke will have there final battle oh & btw naruto is training with bee to take control of the nine tails chakra just like bee
Itachi was ordered by the Hokage to kill his entire clan because he thought the Uchiha clan was a major threat to him. But only Itachi, the Anbu captain that was also involved in some way, and the Hokage knew that. Itachi was going to kill the entire clan, but couldn't bring himself to kill Sasuke as well, because he had a strong bond with him. So Itachi told Sasuke to hate him and to feed off of it, so he could get stronger. Itachi also told Sasuke that if he wanted to get the Mangekyou Sharingan he must kill his best friend. So Itachi ran away, and it is said he cried as he ran. Itachi joined the Akatsuki and waited for the day that Sasuke would come and kill him. Madara later tells Sasuke, after he kills Itachi, that Itachi planned to give him his eyes.
Itachi was very ill before Sauske killed him. The reason why he wanted his brother to kill him was because Itachi wanted Sasuke to be the hero of the hidden leaf village. He wanted Sauake to be the one to avenge his clan. There were a few other reasons as well. Itachi wanted to battle Sasuke to rid his little brother of the cursed mark Orochimaru gave him and he also wanted to give Sasuke some of his powers before he died to protect him from Madara. During Itachi and Sasuke's fight he showed his little brother a way to obtain more power, by taking the eyes of a Uchiha to have light so he wouldn't be blinded after using his eyes too much during battle.