This is just a note for the person who wrote above. The question is how are they related, not are they related! IDIOT! Like uncle, brother . . .what?
That was a really stupid answer, the first person who answered, because Kakashi has a sharingan, but he is not related to Tobi or Itachi.
What you should have said, is they are both related as they are both part of the Uchiha clan. But that still doesn't answer the question.
I don't think anyone knows as I don't think it is written in the manga how they are related, but all I know is Madara (Tobi) is realllllllllly old, (He was around the same time as the 1st Hokage) so he's not Itachi's brother or something like that! x
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He reveals it to Sasuke after Itachi dies. After Sasuke kills Itachi, Madara tells Sasuke about Itachi's hidden life. He also tells Sasuke who he is- Uchiha Madara! This is in Episode 140- fate.
Sasori hidan tobi nagato kisame kohnan zetsu itachi deidara kakuzu orochimaru (former)
well i already know that itachi and Tobi have the kekki genkai of the uchiha...ans ithink pain and his rennagan are a kekki genkai
Sasuke sees Tobi when he fights Deidara. Tobi flees after Deidara self-detonates. However, after he kills Itachi, Sasuke meets Tobi, who reveals himself as Madara Uchiha. The Shipuden Episode is 139.
No...not at all it is her special jutsu , do yu remember when tobi killed her , their was blood coming out of her and that proves it , she uses paper just like itachi uses crows