answersLogoWhite

0


Best Answer

Betahistine

Betahistine hydrochloride is the generic name for the anti vertigo drug SERC. It was first registered in Europe in 1970 for the treatment of Ménière's disease. It is commonly prescribed for people who have balance disorders or to alleviate the vertigo symptoms associated with Ménière's disease.

Betahistine is available in 8mg or 16mg tablets taken 3 times daily. Doses may be adjusted to between 24-48mg a day as needed. It is contraindicated for people with peptic stomach ulcers or tumours of the adrenal gland. People with bronchial Asthma should be closely monitored.

Chemistry and Pharmacokinetics

Betahistine chemically is 2-[2-(methylamino) ethyl] pyridine, and is formulated as the dihydrochloride salt. Is is as close resembling between the structures of betahistine and histamine.

Betahistine comes in a tablet form and should be taken orally. It is rapidly and completely absorbed from its tablet form. The mean plasma half-life is 3-4 hours, and excretion is virtually complete in the urine within 24 hours. Plasma protein binding is very low.

The metabolism of betahistine produced two inactive metabolites, pyriylacetic acid and 2-(2-aminoethyl) pyridine.

User Avatar

Wiki User

15y ago
This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: What is the difference between Betahistine hydrochloride and Betahistine dihydrochloride?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Continue Learning about Chemistry

What is the difference between acetyl l carnitine hydrochloride and acetyl l carnitine?

The mechanism for absorption is improved in the hydrochloride version, but I could be mistaken.


What is the difference between phentermine and phentermine hcl?

Phentermine hcl is short for phentermine hydrochloride, the medically recognized name for the anorexiant drug phentermine. Phentermine Resin is a brand name for one of the manufacturers.


Difference between crack and freebase?

Nothing, both are terms for the free base (as in acid/base in chemistry) form of the cocaine alkaloid. This is obtained by mixing ordinary cocaine hydrochloride salt with an alkali.


What is the difference between cetirizine and hydroxyzine?

Cetirizine has active ingredients of cetirizine hydrochloride. It is used in multiple allergies, idiopathic urticaria, oedema mucosal, rhinitis seasonal, blood pressure abnormal, rhinitis allergic.Hydroxyzine hcl has active ingredients of hydroxyzine hydrochloride. It is used in prophylaxis of nausea and vomiting, rash, depression, prurigo, rash erythematous, nausea.


What is the chemical reaction between cocaine hydrochloride and sodium bicarbonate?

Coc-H+Cl− + NaHCO3 → Coc + H2O + CO2 + NaCl= Crack (Freebase) Cocaine When sodium bicarbonate is heated, it breaks down into carbon dioxide and sodium carbonate. The cocaine molecule contains hydrochloride, which the sodium carbonate reacts to. The reaction strips the cocaine molecule of the hydrochloride, which leaves it as an oily free base, which can be molded into a rock-like shape.

Related questions

What is the difference between Betahistine dihydrochloride and Betahistine mesylate?

The only real difference is the salt from which the medicine is derived. Betahistine dihydrochloride comes from a dihydrochloride salt, and mesilate comes from a mesilate salt.


What is the difference between Cetirizine hydrochloride and Cetirizine dihydrochloride?

The active ingredient in both pills is the same (Cetirizine). The difference between hydrochloride and dihydrochloride is the difference between the non active ingredients in the pills that are added to the drug so that there is enough bulk to make a pill. The above 'advice' is simply rubbish. Any (old Skool) A-Level chemistry student knows the difference between 'hydrochloride' and 'di-hydrochloride': Not the same molecule.However, in layman's terms: cetirizine di-hydrochloride is the real thing and is less likely to make you drowsy. Cetirizine hydrochloride is a copycat molecule to work around patent laws.From personal experience, cetirizine hydrochloride makes me drowsy, whereas cetirizine di-hydrochloride does not. :-)


What is the difference between acetyl l carnitine hydrochloride and acetyl l carnitine?

The mechanism for absorption is improved in the hydrochloride version, but I could be mistaken.


What is the difference between benzocaine and benzocaine hydrochloride?

benzocaine hydrochloride readily dissolves in water and bezocaine is only very slightly soluable in cold water


Can you drink alcohol with Levocetirizine dihydrochloride?

Nothing... I take cetirizine hydrochloride myself - prescribed to alleviate hay fever. To quote the information leaflet from the box the tablets came in... "No significant interactions have been observed between alcohol and cetirizine at the recommended doses. "


What is the difference between Amantadine and Amantadine hydrochloride?

Actually they are the same substance. A chloride ion is introduced to amantadine to become amantadine hydrochloride. This will be helpful to increase the solubility of amantadine. Most drugs are absorbed faster by the body if they are salts, especially hydrochloride salts and sulfate salts


IS there a difference between Oxycontin hcl 5mg and oxycodone ir 5mg?

Yes Oxycontin hydrochloride is a time released tablet and oxycodone ir is an instant release tablet.


What is the difference between phentermine and phentermine hcl?

Phentermine hcl is short for phentermine hydrochloride, the medically recognized name for the anorexiant drug phentermine. Phentermine Resin is a brand name for one of the manufacturers.


Difference between crack and freebase?

Nothing, both are terms for the free base (as in acid/base in chemistry) form of the cocaine alkaloid. This is obtained by mixing ordinary cocaine hydrochloride salt with an alkali.


What is the difference between B Long and B Long F?

I think b-long has only one content called pyridoxine hydrochloride and b-long f has folic acid in addition to ph.


What is the difference between cetirizine and hydroxyzine?

Cetirizine has active ingredients of cetirizine hydrochloride. It is used in multiple allergies, idiopathic urticaria, oedema mucosal, rhinitis seasonal, blood pressure abnormal, rhinitis allergic.Hydroxyzine hcl has active ingredients of hydroxyzine hydrochloride. It is used in prophylaxis of nausea and vomiting, rash, depression, prurigo, rash erythematous, nausea.


What is the difference between avil and cetirizine?

The active ingredient in Cetirizine is Cetirizine hydrochloride. The active ingredient in Avil is pheniramine maleate. Both are used to treat symptoms of allergies. You should ask your pharmacist to confirm this information.