What is a benzopyrene?

What are the uses of the benzopyrene nucleus?

The benzopyrene nucleus is commonly found in polycyclic aromatic hydrocarbons (PAHs) and has been linked to causing DNA damage, mutations, and cancer. It is often used in research to study the effects of environmental pollutants and carcinogens on living organisms.

Is benzopyrene an oxidizing mutagenic agent?

Benzo[a]pyrene is a polycyclic aromatic hydrocarbon and a known carcinogen that can be metabolized into reactive intermediates capable of forming DNA adducts. These adducts can lead to mutations, making benzo[a]pyrene a mutagenic agent. Oxidation can also play a role in the metabolic activation of benzo[a]pyrene, but it is not the primary mechanism for its mutagenicity.

What dangers are posed by gas flaring?

Flaring is a way to burn off excess natural gas during oil production, but the process effectively wastes a natural resource while simultaneously emitting carbon dioxide into the atmosphere. Oil refinery flare stacks may emit methane and other volatile organic compounds as well as sulfur dioxide and other sulfur compounds, which are known to exacerbate asthma and other respiratory problems. Other emissions include, aromatic hydrocarbons (benzene, toluene, xylene) and benzopyrene. Gas flaring is related to acid rain, crop failure, water pollution and a decline in the populations of many species of animals.

What Chemical as affect on body when smoking?

Acetone( used in nail polish remover), methanol(used as fuel for torches), nicotene(poison), cyanide(used as insect killer), ammonia( bathroom cleaner), formaldehyde(used as dead tissue preservative), carbon mononoxide(used as an anti-freeze in cars), and acetylene( found in car exhaust) NEVER SMOKE

What happens if you smoke?

The effects of smoking on human health are serious and in many cases, deadly. There are approximately 4,000 chemicals in cigarettes, hundreds of which are toxic. The ingredients in cigarettes affect everything from the internal functioning of organs to the efficiency of the body's immune system. The effects of cigarette smoking are destructive and widespread. Smoking Effects on the Human BodyToxic ingredients in cigarette smoke travel throughout the body, causing damage in several different ways.Nicotine reaches the brain within 10 seconds after smoke is inhaled. It has been found in every part of the body and in breast milk.Carbon monoxide binds to hemoglobin in red blood cells, preventing affected cells from carrying a full load of oxygen.Cancer-causing agents (carcinogens) in tobacco smoke damage important genes that control the growth of cells, causing them to grow abnormally or to reproduce too rapidly.The carcinogen benzopyrene binds to cells in the airways and major organs of smokers.Smoking affects the function of the immune system and may increase the risk for respiratory and other infections.There are several likely ways that cigarette smoke does its damage. One is oxidative stress that mutates DNA, promotes atherosclerosis, and leads to chronic lung injury. Oxidative stress is thought to be the general mechanism behind the aging process, contributing to the development of cancer, cardiovascular disease, and COPD.The body produces antioxidants to help repair damaged cells. Smokers have lower levels of antioxidants in their blood than do nonsmokers.Smoking is associated with higher levels of chronic inflammation, another damaging process that may result in oxidative stress. I hope this is helpful guys!

What is the chemical composition of marijuana?

Marijuana contains over 100 different cannabinoids, with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) being the most well-known. It also contains terpenes, flavonoids, and other compounds that contribute to its effects.

What are the health benefits of rosemary herbs?

Rosemary has antioxidant and anti-inflammatory properties that help support the immune system and reduce inflammation. It also contains compounds that may improve digestion, enhance memory, and promote hair growth. Additionally, rosemary is rich in vitamins and minerals that support overall health and well-being.

Can magic mushrooms cause permanent damage?

Marijuana has no physical damage to a user and it does not kill brain cells. It is not addictive. No hang over no psycho behavior like alcohol. It is way better to smoke than tobacco. It is legal to have in California if you have a medical license. If you don't it is still not a crime, never illegal in California since 2003. It is decriminalized in the whole state of CALIFORNIA. Eventually it will be decriminalized state wide by Obama. No damage has ever been reported nor an over dose. you can't over dose but you can overdose on alcohol. A lot of people get alcohol poisoning but continue to drink, ew. The most annoying part is only when i read on the internet that some Americans love to spread false rumors about it being a dangerous drug that is not legal anywhere. Um have you ever traveled outside the country? The rest of the world giggles at that. LEGAL IN BRITSH COLUMBIA, HOLLAND,PERU,MEXICO,CZECH REPUBLIC and some islands. It is only illegal in the USA, Turkey and some parts of the middle east. I'm glad the USA can agree with turkey and the middle east on something, ha or not. It offers neuroprotection, meaning it protects nerves and brain cells. There is also some evidence that it may facilitate brain cell development. The US DHS confirms the scientific research that marijuana can be used as a neuroprotectant and antioxidant, it hold the patent to these uses patent no. 6630507 I can also relive the symptoms of ADD and ADHD as well as help motivate them to do their work. The consequences of minimal usage are not alarming. Many voices on the subject overplay the impact marijuana has in the development of the brain as not all users are taking the drug every week. A brief outline of these effects on the brain is as follows: User's are more likely to develop mental problems such as anxiety, depression, etc. This, however, is a varying risk from person to person. Some people may never experience these mental issues. Short term memory issues is also a common problem linked with the drug, but this is only temporary. People can sometimes identify someone who abuses the drug by their behaviour. The main problem with marijuana is that people think that the drug is relatively harmless. This is only true if the user doesn't abuse the drug. I know people who smoke it before they go to bed (marijuana is a great for insomnia relief and other debilitating conditions) and when they wake up (certain strains can be more effective than coffee and are much less addictive than coffee). It can happen to anyone. Weed is a known bronchodialator to the medical community. This being said it could be effective treatment to a person with asthma as long as they vape, rather than smoke. Smoking deposits tar into the lungs. Because marijuana smoke is rarely filtered this can be up to 4 times as much tar by weight smoked than cigarette smoke deposits, this being said a tobacco smoker goes through 20-40 cigarettes a day while a stoner goes through 2-4 joints of the same weight per day. Marijuana smoke also causes temporary irritation, but it has no lasting effects. Marijuana does not increase your risk for cancer or COPD, let alone cause them unlike tobacco smoking and there are studies that conclusively prove this and disprove the myth and lie alleged by the negative propaganda.

How does marijuana effect people?

Cannabis has little effect on someones health. About the only negative effect cannabis has is when you smoke it, it can be harmful to your lungs. But other than that it can also have positive effects on peoples health which is why it is now being used medically. It is used to stimulate someone to eat as well as a variety of other uses. The largest study of the health effects of marijuana to date was done by Kaiser Permanente. They studied the health records of 65,000 patients over a number of years. They found no significant differences between the health histories of those who smoked pot versus those who did not smoke marijuana. Marijuana and Mortality Every major government commission report on marijuana from around the world over the last 100 years has concluded that marijuana prohibition was based on racism, ignorance, and nonsense. They all said the marijuana laws should have been repealed long ago because they do more harm than good.They all said that marijuana is not a significant threat to health. Major Studies of Drugs and Drug Policy.

What are reasons for smoking not to be advertised?

he rationale for smoking bans posits that smoking is optional, whereas breathing is not. Therefore, proponents say, smoking bans exist to protect breathing people from the effects of second-hand smoke, which include an increased risk of heart disease, cancer, emphysema, and other diseases.[2][3] Laws implementing bans on indoor smoking have been introduced by many countries in various forms over the years, with some legislators citing scientific evidence that shows tobacco smoking is harmful to the smokers themselves and to those inhaling second-hand smoke.In addition, such laws may reduce health care costs,[4] improve work productivity, and lower the overall cost of labour in the community thus protected, making that workforce more attractive for employers. In the US state of Indiana, the economic development agency included in its 2006 plan for acceleration of economic growth encouragement for cities and towns to adopt local smoking bans as a means of promoting job growth in communities.Additional rationales for smoking restrictions include reduced risk of fire in areas with explosive hazards; cleanliness in places where food, pharmaceuticals, semiconductors, or precision instruments and machinery are produced; decreased legal liability; potentially reduced energy use via decreased ventilation needs; reduced quantities of litter; healthier environments; and giving smokers incentive to quit.[5]The World Health Organization considers smoking bans to have an influence to reduce demand for tobacco by creating an environment where smoking becomes increasingly more difficult and to help shift social norms away from the acceptance of smoking in everyday life. Along with tax measures, cessation measures, and education, smoking bans are viewed by public health experts as an important element in reducing smoking rates and promoting positive health outcomes. When effectively implemented they are seen as an important element of policy to support behaviour change in favour of a healthy lifestyle.[6]Medical and scientific basis for smoking restrictionsMain article: Passive smoking Research has generated evidence that second-hand smoke causes the same problems as direct smoking, including lung cancer, cardiovascular disease, and lung ailments such as emphysema, bronchitis, and asthma.[7] Specifically, meta-analyses show that lifelong non-smokers with partners who smoke in the home have a 20-30% greater risk of lung cancer than non-smokers who live with non-smokers. Non-smokers exposed to cigarette smoke in the workplace have an increased lung cancer risk of 16-19%.[8]A study issued in 2002 by the International Agency for Research on Cancer of the World Health Organization concluded that non-smokers are exposed to the same carcinogens on account of tobacco smoke as active smokers.[9] Sidestream smoke[10] contains 69 known carcinogens, particularly benzopyrene[11] and other polynuclear aromatic hydrocarbons, and radioactive decay products, such as polonium 210.[12] Several well-established carcinogens have been shown by the tobacco companies' own research to be present at higher concentrations in second-hand smoke than in mainstream smoke.[13]Scientific organisations confirming the effects of second-hand smoke include the U.S. National Cancer Institute,[14] the U.S. Centers for Disease Control and Prevention (CDC),[15] the U.S. National Institutes of Health,[16] the Surgeon General of the United States,[17] and the World Health Organization.[18]Air qualityRestrictions upon smoking in bars and restaurants can substantially improve the air quality in such establishments. For example, one study listed on the website of the U.S. Centers for Disease Control and Prevention states that New York's statewide law to eliminate smoking in enclosed workplaces and public places substantially reduced RSP (respirable suspended particles) levels in western New York hospitality venues. RSP levels were reduced in every venue that permitted smoking before the law was implemented, including venues in which only second-hand smoke from an adjacent room was observed at baseline.[19] The CDC concluded that their results were similar to other studies which also showed substantially improved indoor air quality after smoking bans were instituted. A 2004 study showed New Jersey bars and restaurants had more than nine times the levels of indoor air pollution of neighbouring New York City, which had already enacted its smoking ban.[20]Research has also shown that improved air quality translates to decreased toxin exposure among employees.[21] For example, among employees of the Norwegian establishments that enacted smoking restrictions, tests showed improved (i.e. decreased) levels of nicotine in the urine of both smoking and non-smoking workers (as compared with measurements prior to going smoke-free).[22]Public Health Law ResearchIn 2009, the journal Public Health Law Research published an evidence brief summarising the research assessing the effect of a specific law or policy on public health. They stated that "There is strong evidence supporting smoking bans and restrictions as effective public health interventions aimed at decreasing exposure to secondhand smoke."[23] HistorySee also: List of smoking bans Smoking bans worldwide as of June 2011: no ban (or no data)patchy and incomplete ban, low enforcementno national ban, some localities have comprehensive bannational ban in public areas except entertainment and restaurants, or weak enforcement in indoor entertainment areasnational ban in public areas except entertainment and restaurants, some localities have comprehensive bansnational ban in all public indoor areas with some exceptionsNote: Countries with all subnational entities enacting a smoking ban equates to a nationwide ban here, such as for Canada and Australia1973 and 2007 ABC news reports on the initial, and then the complete, indoor smoking bans in Victoria, Australia.One of the world's earliest smoking bans was a 1575 Mexican ecclesiastical council regulation which forbade the use of tobacco in any church in Mexico and Spanish colonies in the Caribbean. In 1604, King James I of England published an anti-smoking treatise, A Counterblaste to Tobacco, that had the effect of raising taxes on tobacco. The Ottoman Sultan Murad IV prohibited smoking in his empire in 1633.[24] Pope Urban VII also prohibited smoking in the Church in 1590[25] followed by Urban VIII in 1624.[24] Pope Urban VII in particular threatened to excommunicate anyone who "took tobacco in the porchway of or inside a church, whether it be by chewing it, smoking it with a pipe or sniffing it in powdered form through the nose".[26] The earliest citywide European smoking bans were enacted shortly thereafter. Such bans were enacted in Bavaria, Kursachsen, and certain parts of Austria in the late 17th century. Smoking was banned in Berlin in 1723, in Königsberg in 1742, and in Stettin in 1744. These bans were repealed in the revolutions of 1848.[27] The first building in the world to ban smoking was the Old Government Building in Wellington, New Zealand in 1876. This was over concerns about the threat of fire, as it is the second largest wooden building in the world.[28]The first modern attempt at restricting smoking was imposed by the then German government in every university, post office, military hospital, and Nazi Party office, under the auspices of Karl Astel's Institute for Tobacco Hazards Research, created in 1941 under orders from Adolf Hitler.[29] Major anti-tobacco campaigns were widely broadcast by the Nazis until the demise of the regime in 1945.[30]In the latter part of the 20th century, as research on the risks of second-hand tobacco smoke became public, the tobacco industry launched "courtesy awareness" campaigns. Fearing reduced sales, the industry created a media and legislative programme that focused upon "accommodation". Tolerance and courtesy were encouraged as a way to ease heightened tensions between smokers and those around them, while avoiding smoking bans. In the USA, states were encouraged to pass laws providing separate smoking sections.[31]In 1975, the US state of Minnesota enacted the Minnesota Clean Indoor Air Act, making it the first state to restrict smoking in most public spaces. At first, restaurants were required to have No Smoking sections, and bars were exempt from the Act.[32] As of 1 October 2007, Minnesota enacted a ban on smoking in all restaurants and bars statewide, called the Freedom to Breathe Act of 2007.[33]The resort town of Aspen, Colorado, became the first city in the US to restrict smoking in restaurants, in 1985.[34]On April 3, 1987, the City of Beverly Hills, California, initiated an ordinance to restrict smoking in most restaurants, in retail stores and at public meetings. It exempted restaurants in hotels - City Council members reasoned that hotel restaurants catered to large numbers of visitors from abroad, where smoking is more acceptable than in the United States.In 1990, the city of San Luis Obispo, California, became the first city in the world to restrict indoor smoking in all public places, including bars and restaurants.[35]In America, California's 1998 smoking ban encouraged other states such as New York to implement similar regulations. California's ban included a controversial restriction upon smoking in bars, extending the statewide ban enacted in 1994. As of April 2009 there were 37 states with some form of smoking ban.[36] Some areas in California began banning smoking across whole cities, including every place except residential homes. More than 20 cities in California enacted park and beach smoking restrictions.Since December 1993, in Peru, it is illegal to smoke in any public enclosed places and any public transport vehicles (according to Law 25357 issued on Nov 27, 1991 and its regulations issued on Nov 25, 1993 by decree D.S.983-93-PCM). There is also legislation restricting publicity, and it is also illegal (Law 26957 May 21, 1998) to sell tobacco to minors or directly advertise tobacco within 500m of schools (Law 26849 Jul 9, 1997).On 3 December 2003, New Zealand passed legislation to progressively implement a smoking ban in schools, school grounds, and workplaces by December 2004.[37] On 29 March 2004, Ireland implemented a nationwide ban on smoking in all workplaces. In Norway, similar legislation was put into force on 1 June the same year.Smoking was banned in all public places in the whole of the United Kingdom in 2007, when England became the final region to have the legislation come into effect (the age limit for buying tobacco was also raised from 16 to 18 on 1 October 2007).July 12, 1999 a Division Bench of the Kerala High Court in India banned smoking in public places by declaring ``public smoking as illegal first time in the history of whole world, unconstitutional and violative of Article 21 of the Constitution .The Bench headed by Dr. Justice K. Narayana Kurup, held that ``tobacco smoking in public places (in the form of cigarettes, cigars, beedies or otherwise) ``falls within the mischief of the penal provisions relating to public nuisance as contained in the Indian Penal Code and also the definition of air pollution as contained in the statutes dealing with the protection and preservation of the environment, in particular, the Air (Prevention and Control of Pollution), Act 1981. AFP: Nepal to ban smoking in public places On 31 May 2011 Venezuela introduced a restriction upon smoking in enclosed public and commercial spaces.[38]Smoking was first restricted in schools, hospitals, trains, buses and train stations in Turkey in 1996. In 2008, a more comprehensive smoking ban was implemented, covering all all public indoor venues.Smoking has been restricted at a French beach - the Plage Lumière in La Ciotat, France, became the first beach in Europe[39] to restrict smoking, from August 2011, in an effort to encourage more tourists to visit the beach.Cigarette advertisingIn several parts of the world, tobacco advertising and sponsorship of sporting events is prohibited. The bar upon tobacco advertising and sponsorship in the European Union in 2005 prompted Formula One Management to look for venues that permit display of the livery of tobacco sponsors, and led to some of the races on the calendar being cancelled in favor of more 'tobacco-friendly' markets. As of 2008, only one Formula One team, Scuderia Ferrari, received sponsorship from a tobacco company. Marlboro branding appeared on its cars in two races; Monaco and China, as neither restricts tobacco advertising. Despite the EU prohibition from 2005, advertising bill-boards for tobacco were still in use in Germany as of 2012. MotoGP team Ducati Marlboro received sponsorship from Marlboro, its branding appearing at races in Qatar and China. On 1 July 2009 Ireland prohibited the advertising and display of tobacco products in all retail outlets; when fully implemented, this will mean that shops will have to store cigarettes in closed containers out of sight of customers.Public support for smoking bansA 2007 Gallup poll found that 54% of Americans favoured completely smoke-free restaurants, 34% favoured completely smoke-free hotel rooms, and 29% favoured completely smoke-free bars.[40] Another Gallup poll, of over 26,500 Europeans, conducted in December 2008, found that "a majority of EU citizens support smoking bans in public places, such as offices, restaurants and bars." The poll further found that "support for workplace smoking restrictions is slightly higher than support for such restrictions in restaurants (84% vs. 79%). Two-thirds support smoke-free bars, pubs and clubs." The support is highest in countries which have implemented clear smoking bans: "Citizens in Italy are the most prone to accept smoking restrictions in bars, pubs and clubs (93% - 87% "totally in favour"). Sweden and Ireland join Italy at the higher end of the scale with approximately eight out of 10 respondents supporting smoke-free bars, pubs and clubs (70% in both countries is totally in favor)."[41]Effects of smoking bansEffects upon healthSeveral studies have documented health and economic benefits related to smoking bans. In the first 18 months after Pueblo, Colorado enacted a smoking ban in 2003, hospital admissions for heart attacks dropped by 27% while admissions in neighbouring towns without bans showed no change. The decline in heart attacks was attributed to the ban, which reduced exposure to second-hand smoke.[42] A similar study in Helena, Montana found a 40% reduction in heart attacks following the imposition of a smoking ban.[43] However, a 2010 study comparing US nationwide data suggested that smoking bans may not be associated with statistically significant short-term declines in mortality or hospital admissions for myocardial infarction or other diseases.[44] Researchers at the University of Dundee found significant improvements in bar workers' lung function and inflammatory markers attributed to the introduction of Ireland's smoking ban; the benefits were particularly pronounced for bar workers with asthma.[45] The Bar Workers' Health and Environment Tobacco Smoke Exposure (BHETSE) study found the percentage of all workers reporting respiratory symptoms, such as wheezing, shortness of breath, cough and phlegm production, fell from 69% to 57%.[46] A group of researchers from Turin, Italy found that smoking restrictions had significantly reduced heart attacks in the city, and attributed most of the reduction to decreased second-hand smoke exposure.[47] A comprehensive smoking ban in New York was found to have prevented 3,813 hospital admissions for heart attacks in 2004, and to have saved $56 million in health-care costs for the year.[48]A study in England estimated a 2.4% reduction in heart attack emergency admissions to hospital (or 1,200 fewer admissions) in the 12 months following the implementation of the national smoking ban.[49][50]Effects upon tobacco consumptionSmoking bans are generally acknowledged to reduce rates of smoking; smoke-free workplaces reduce smoking rates among workers,[51] and restrictions upon smoking in public places reduce general smoking rates through a combination of stigmatisation and reduction in the social cues for smoking.[52] However, reports in the popular press after smoking bans have been enacted often present conflicting accounts as regards perceptions of effectiveness. One report stated that cigarette sales in Ireland and Scotland increased after their smoking bans were implemented.[53] In contrast, another report states that in Ireland, cigarette sales fell by 16% in the six months after implementation of the ban.[54] In the UK, cigarette sales fell by 11% during July 2007, the first month of the nationwide smoking ban, compared with July 2006.[55]A 1992 document from Phillip Morris summarised the tobacco industry's concern about the effects of smoking bans: "Total prohibition of smoking in the workplace strongly effects [sic] tobacco industry volume. Smokers facing these restrictions consume 11%-15% less than average and quit at a rate that is 84% higher than average."[56]In the United States, the CDC reported a levelling-off of smoking rates in recent years despite a large number of ever more comprehensive smoking bans and large tax increases. It has also been suggested that a "backstop" of hardcore smokers has been reached: those unmotivated and increasingly defiant in the face of further legislation.[57]In Sweden, use of snus, as an alternative to smoking, has risen steadily since that nation's smoking ban.[58]Smoking restrictions may make it easier for smokers to quit. A survey suggests 22% of UK smokers may have considered quitting in response to that nation's smoking ban.[59]Restaurant smoking restrictions may help to stop young people from becoming habitual smokers. A study of Massachusetts youths, found that those in towns with smoking bans were 35 percent less likely to be habitual smokers.[60][61]Effects upon businessesSmoking is forbidden on some streets in Japan. Smokers utilise smoking lounges, such as this one in Tokyo. A sign stating "Please do not smoke while walking" in Taitō, TokyoMany studies have been published in the health industry literature on the economic effect of smoking bans. The majority of these government and academic studies have found that there is no negative economic impact associated with smoking restrictions and many findings that there may be a positive effect on local businesses.[62] A 2003 review of 97 such studies of the economic effects of a smoking ban on the hospitality industry found that the "best-designed" studies concluded that smoking bans did not harm businesses.[63]Studies funded by the bar and restaurant associations have sometimes claimed that smoking bans have a negative effect on restaurant and bar profits. Such associations have also criticised studies which found that such legislation had no impact.[64]The following are some examples: the Dallas Restaurant Association funded a study that showed a $11.8 million decline in alcohol sales ranging from 9 to 50% in Denton, Texas. A 2004 study by Ridgewood Economic Associates LTD funded by the Empire State Restaurant and Tavern Association found a loss of 2000 jobs, $28.5 million dollar loss in wages, and a loss of $37 million in New York State product.[65] A 2004 study for the National Restaurant Association of the United States conducted by Deloitte and Touche found a significant negative impact. The restaurant Association of Maryland found sales tax receipts for establishments falling 11% in their study. Carroll and Associates found bars sales decreased by 18.7% to 24.3% in a number of Ontario markets following banning smoking in bars.[66] The Buckeye Liquor Permit Holders Association reported that liquor sales were down over $67 million dollars while sales for home consumption increased and asked for the smoking ban to be amended in Ohio.[67]AustraliaA government survey in Sydney found that the proportion of the population attending pubs and clubs rose after smoking was banned inside them.[68] However, a ClubsNSW report in August 2008 blamed the smoking ban for New South Wales clubs suffering their worst fall in income ever, amounting to a decline of $385 million. Income for clubs was down 11% in New South Wales. Sydney CBD club income fell 21.7% and western Sydney clubs lost 15.5%.[69]GermanySmoking restrictions were introduced in German hotels, restaurants, and bars in 2008 and early 2009. The restaurant industry has claimed that some businesses in the states which banned smoking in late 2007 (Lower Saxony, Baden-Württemberg, and Hessen) experienced reduced profits. The German Hotel and Restaurant Association (DEHOGA) claimed that the smoking ban deterred people from going out for a drink or meal, stating that 15% of establishments that adopted a ban in 2007 saw turnover fall by around 50%.[70] However, a study by the University of Hamburg (Ahlfeldt and Maennig 2010) finds negative impacts on revenues, if any, only in the very short run. In the medium and long run, a recovery of revenues took place. These results suggest either, that the consumption in bars and restaurants is not affected by smoking bans in the long run, or, that negative revenue impacts by smokers are compensated by increasing revenues through non-smokers.[71] Smoking is not permitted in any public transit or in or around railway stations except for the locations expressly indicated for smoking. Smoking on trains itself was prohibited completely by the Deutsche Bahn AG in 2007, and there was a permanent reduction of smoking compartments on all trains in 2000.[72] Smoking has restricted in airports and all Lufthansa planes since the late 1990s.[73]In 2008, Bavaria was the first federal state of Germany to restrict smoking in every bar and restaurant. After this restriction was criticised as being "too hard" by some members of the governing party CSU, it was relaxed one year later. Supporters of smoking bans then brought about a public referendum on the issue, which led to even firmer restrictions than the initial ban. Thereafter a more comprehensive ban was introduced in 2010.[74]IrelandIn Ireland, the main opposition was from publicans. Ireland was the world's first country to introduce fully smoke-free workplaces. The Irish workplace smoke-free law was introduced with the intention of protecting workers from second-hand smoke and to discourage smoking in a nation with a high percentage of smokers. Many pubs introduced "outdoor" arrangements (generally heated areas with shelters). It was speculated by opponents that the smoke-free workplaces law would increase the amount of drinking and smoking in the home, but recent studies showed this was not the case.[75]Ireland's Office of Tobacco Control website indicates that "an evaluation of the official hospitality sector data shows there has been no adverse economic effect from the introduction of this measure (the March 2004 national introduction of smoke-free in bars, restaurants, etc). It has been claimed that the smoke-free law was a significant contributing factor to the closure of hundreds of small rural pubs, with almost 440 fewer licences renewed in 2006 than in 2005.[76]Isle of ManSmoke-free restrictions came into effect in the Isle of Man on 30 March 2008.IndiaJuly 12, 1999 a Division Bench of the Kerala High Court in India banned smoking in public places by declaring ``public smoking as illegal first time in the history of whole world, unconstitutional and violative of Article 21 of the Constitution .The Bench headed by Dr. Justice K. Narayana Kurup, held that ``tobacco smoking in public places (in the form of cigarettes, cigars, beedies or otherwise) ``falls within the mischief of the penal provisions relating to public nuisance as contained in the Indian Penal Code and also the definition of air pollution as contained in the statutes dealing with the protection and preservation of the environment, in particular, the Air (Prevention and Control of Pollution), Act 1981. AFP: Nepal to ban smoking in public places On 31 May 2011 Venezuela introduced a restriction upon smoking in enclosed public and commercial spaces.United KingdomAn English/Welsh no smoking sign at a railway station Smoke-free regulations came into effect in Scotland on 26 March 2006,[77] in Wales on 2 April 2007, in Northern Ireland on 30 April 2007 and in England on 1 July 2007.[78] The legislation was cited as an example of good regulation which has had a favourable impact on the UK economy by the Department of Business Innovation and Skills [79] and a review of the impact of smoke-free legislation carried out for the Department of Health concluded that there was no clear adverse impact on the hospitality industry[80] despite initial criticism from some voices within the pub trade.Six months after implementation in Wales, the Licensed Victuallers Association (LVA), which represents pub operators across Wales, claimed that pubs had lost up to 20% of their trade. The LVA said some businesses were on the brink of closure, others had already closed down, and there was little optimism trade would eventually return to previous levels.[81]The British Beer and Pub Association (BBPA), which represents some pubs and breweries across the UK claimed that beer sales were at their lowest level since the 1930s, ascribing a fall in sales of 7% during 2007 to the smoke-free regulations.[82]According to a survey conducted by pub and bar trade magazine The Publican, the anticipated increase in sales of food following intrduction of smoke-free workplaces did not immediately occur. The trade magazine's survey of 303 pubs in the United Kingdom found the average customer spent £14.86 on food and drink at dinner in 2007, virtually identical to 2006.[83]A survey conducted by BII (formerly British Institute of Innkeeping) and the Federation of Licensed Victuallers' Associations (FLVA) concluded that sales had decreased by 7.3% in the 5 months since the introduction of smoke-free workplaces on 1 July 2007. Of the 2,708 responses to the survey, 58% of licensees said they had seen smokers visiting less regularly, while 73% had seen their smoking customers spending less time at the pub.[84]The data suggesting a negative impact on pubs is partly explained by the reclassified of some as restaurants when serving food becomes the prime source of income. As a result, while the number of premises described as pubs went down following the implementation of the legislation, the total number of premises licensed to sell alcohol went up.[85]United StatesSee also: List of smoking bans in the United States In the USA, smokers and hospitality businesses initially argued that businesses would suffer from smoke-free laws. However, a 2006 review by the U.S. Surgeon General found that smoking restrictions were unlikely to harm businesses in practice, and that many restaurants and bars might see increased business.[86][87]In 2003, New York City amended its smoke-free law to include all restaurants and bars, including those in private clubs, making it, along with the California smoke-free law, one of the toughest in the United States. The city's Department of Health found in a 2004 study that air pollution levels had decreased sixfold in bars and restaurants after the restrictions went into effect, and that New Yorkers had reported less second-hand smoke in the workplace. The study also found the city's restaurants and bars prospered despite the smoke-free law, with increases in jobs, liquor licenses, and business tax payments. The President of the New York nightlife association remarked that the study was not wholly representative, as by not differentiating between restaurants and nightclubs, the reform may have caused businesses like nightclubs and bars to suffer instead.[88] A 2006 study by the New York State Department of Health found similar results: "(...) the CIAA has not had any significant negative financial effect on restaurants and bars in either the short or the long term."[89]Effects upon musical instrumentsBellows-driven instruments - such as the accordion, concertina, melodeon and Uilleann (or Irish) bagpipes - reportedly need less frequent cleaning and maintenance as a result of the Irish smoke-free law.[90] Effects of prison smoking restrictionsPrisons are increasingly restricting tobacco smoking.[91] In the United States, some states with smoke-free prison policies only prohibit indoor smoking whereas others disallow smoking on the entire prison grounds.[92] In July 2004 the Federal Bureau of Prisons adopted a smoke-free policy for its facilities.[93] A 1993 Supreme Court ruling acknowledged that a prisoner's exposure to second-hand smoke could be regarded as cruel and unusual punishment (which would be in violation of the Eighth Amendment).[94] A 1997 ruling in Massachusetts established that prison smoking bans do not constitute cruel and unusual punishment.[95] Many officials view prison smoking bans as a means of reducing health-care costs.[96] Prison officials and guards are sometimes worried due to previous events in other prisons concerning riots, fostering a cigarette black market within the prison, and other problems resulting from total prison smoking restrictions. Prisons have experienced riots when placing smoking restrictions into effect resulting in prisoners setting fires, destroying prison property, persons being assaulted, injured, and stabbed. One prison in Canada had some guards reporting breathing difficulties from the fumes of prisoners smoking artificial cigarettes made from nicotine patches lit by creating sparks from inserting metal objects into electrical outlets.[97][98] For example in 2008, the Orsainville Detention Centre near Quebec City, withdrew its smoke-free provision following a riot. But the feared increase in tension and violence expected in association with smoking restrictions has generally not been experienced in practice.[95]ComplianceThe introduction of smoking restrictions occasionally generates protests[99] and predictions of widespread non-compliance, and media stories regarding the rise of clandestine smokeasies, including in New York City,[100] Northern Ireland,[101][102] Germany,[103] Illinois,[104] the United Kingdom,[105] Utah,[106] and Washington, D.C.[107] In reality, however, high levels of compliance with smoke-free laws (in excess of 90 per cent) have been reported in most jurisdictions including New York,[108] Ireland,[109] Italy[110] and Scotland.[111] Poor compliance was reported in Kolkata.[112]Criticism of smoke-free lawsSmoke-free regulations and ordinances have been criticised on a number of grounds. Government interference with personal lifestyleCritics of smoke-free provisions, including musician Joe Jackson,[113] and political essayist Christopher Hitchens,[114][115] have claimed that regulation efforts are misguided. Typically, such arguments are based upon an interpretation of John Stuart Mill's harm principle which perceives smoke-free laws as an obstacle to tobacco consumption per se, rather than a bar upon harming other people. Such arguments, which usually refer to the notion of personal liberty, have themselves been criticised by Nobel Prize-winning economist Amartya Sen who defended smoke-free regulations on several grounds.[116] Among other things, Sen argued that while a person may be free to acquire the habit of smoking, they thereby restrict their own freedom in the future given that the habit of smoking is hard to break.[116] Sen also pointed out the heavy costs that smoking inevitably imposes on every society which grants smokers unrestricted access to public services (which, Sen noted, every society that is not "monstrously unforgiving" would do).[116] Arguments which invoke the notion of personal liberty against smoke-free laws are thus incomplete and inadequate, according to Sen.[116]Property rightsSome critics of smoke-free laws emphasise the property rights of business owners, drawing a distinction between nominally public places (such as government buildings) and privately-owned establishments (such as bars and restaurants). Citing economic efficiency, some economists suggest that the basic institutions of private property rights and contractual freedom are capable of resolving conflicts between the preferences of smokers and those who seek a smoke-free environment, without government intrusion.[117] Legality of smoke-free regulationsBusinesses affected by smoke-free regulations have filed lawsuits claiming that these are unconstitutional or otherwise illegal. In the United States, some cite unequal protection under the law while others cite loss of business without compensation, as well as other types of challenges. Some localities where hospitality businesses filed lawsuits against the State or local government include, Nevada, Montana, Iowa, Colorado, Kentucky, New York, South Carolina, and Hawaii.[118][119][120][121][122][123][124][125] Such lawsuits have generally been unsuccessful. Smoke-free laws may move smoking elsewhereRestrictions upon smoking in offices and other enclosed public places often result in smokers going outside to smoke, frequently congregating outside doorways. Many jurisdictions that have restricted smoking in enclosed public places have extended provisions to cover areas within a fixed distance of entrances to buildings.[126] The former British Secretary of State for Health John Reid claimed that restrictions upon smoking in public places may lead to more smoking at home.[127] However, both the House of Commons Health Committee and the Royal College of Physicians disagreed, with the former finding no evidence to support Reid's claim after studying Ireland,[127] and the latter finding that smoke-free households increased from 22% to 37% between 1996 and 2003.[128]In January 2010, the mayor of Boston, Massachusetts, Thomas Menino, proposed a restriction upon smoking inside public housing apartments under the jurisdiction of the Boston Housing Authority.[129][130]Connection to DUI fatalitiesIn May 2008, research published by Adams and Cotti in the Journal of Public Economics examined statistics of drunken-driving fatalities and accidents in areas where smoke-free laws have been implemented in bars and found that fatal drunken-driving accidents increased by about 13 percent, or about 2.5 such accidents per year for a typical county of 680,000. They speculate this could be caused by smokers driving farther away to jurisdictions without smoke-free laws or where enforcement is lax. No evidence is presented for jurisdictions where smoke-free laws and enforcement thereof are consistent.[131] Effects of funding on research literatureAs in other areas of research, the effect of funding on research literature has been discussed with respect to smoke-free laws. Most commonly, studies which found few or no positive and/or negative effects of smoke-free laws and which were funded by tobacco companies have been delegitimised because they were seen as biased in favor of their funders.[132] Professor of Economics at the California State Polytechnic University-San Luis Obispo, Michael L. Marlow, defended "tobacco-sponsored" studies arguing that all studies merited "scrutiny and a degree of skepticism," irrespective of their funding. He wished for the basic assumption that every author were "fair minded and trustworthy, and deserves being heard out" and for less attention to research funding when evaluating the results of a study. Marlow suggests that studies funded by tobacco companies are viewed and dismissed as "deceitful,"[133] i.e. as being driven by (conscious) bad intention.Alternatives to smoke-free lawsIncentives for voluntarily smoke-free establishmentsDuring the debates over the Washington, DC, smoke-free law, city council member Carol Schwartz proposed legislation that would have enacted either a substantial tax credit for businesses that chose to voluntarily restrict smoking or a quadrupling of the annual business license fee for bars, restaurants and clubs that wished to allow smoking. Additionally, locations allowing smoking would have been required to install specified high-performance ventilation systems.[134] VentilationCritics of smoke-free laws have suggested that ventilation is a means of reducing the harmful effects of second-hand smoke. A tobacco industry-funded study conducted by the School of Technology of the University of Glamorgan in Wales, published in the Building Services Journal suggested that "ventilation is effective in controlling the level of contamination", although "ventilation can only dilute or partially displace contaminants and occupational exposure limits are based on the 'as low as reasonably practicable' principle".[135][136] Some hospitality organisations have claimed that ventilation systems could bring venues into line with smoke-free restaurant ordinances. A study published by the American Society of Heating, Refrigerating and Air-Conditioning Engineers and funded by the Robert Wood Johnson Foundation found one establishment with lower air quality in the non-smoking section, due to improperly installed ventilation systems. They also determined that even properly functioning systems "are not substitutes for smoking bans in controlling environmental smoke exposure."[137]The tobacco industry has focused on proposing ventilation as an alternative to smoke-free laws, though this approach has not been widely adopted in the U.S. because "in the end, it is simpler, cheaper, and healthier to end smoking."[138] The Italian smoke-free law ban permits dedicated smoking rooms with automatic doors and smoke extractors. Nevertheless, few Italian establishments are creating smoking rooms due to the additional cost.[139]A landmark report from the U.S. Surgeon General found that even the use of elaborate ventilation systems and smoking

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