She probably likes you. Or maybe her hands are bored, but I would find that less likely.
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It usually means that she wants you to hold her hand; she wants to be close to you.
If you're not together already, she's probably trying to subtly hint that she's interested.
It could mean she is flirting, showing affection, or trying to comfort you. The context and her body language will provide more clues to her intentions.