No, not at all. IF you happen to have an allergic reation to it, it will more than likely manifest itself in the form of a panic or anxiety attack. I've smoked heavily for about 9 years, and I only wish it would plump up my thin lips!
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Yes, mine have begun to swell after smoking my pipe. It might just be certain strains so I am trying to figure this out. However, immediately after taking a hit my lips swell, my husband watched it happen.