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The Short answer is yes. Even in a 410 gauge shotgun with a full choke. Remember that a "410" is 41 caliber or .41 inches in diameter. oo buckshot is only about .32 inches in diameter.
The same is true for shooting slugs in a shotgun. There is no safety issue involved. You will notice that there is no warning on the packaging of the ammunition. In our litigious times you can be sure that if there was a problem there would be a warning printed on the box.
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