To calculate the maintenance dose in controlled release tablets, consider the desired therapeutic concentration, dosing interval, and half-life of the drug. The goal is to maintain a steady-state plasma concentration within the therapeutic range over the dosing interval. This can be achieved by adjusting the dose and release characteristics of the tablet formulation. Consulting pharmacokinetic principles and conducting in vitro and in vivo studies can help optimize the maintenance dose for controlled release tablets.
I have never heard this. It's usually 'like a dose of salts', meaning fast and thoroughly. 'She arrived with a basket of cleaning supplies and went through the house like a dose of salts.'
The margin of safety is calculated by dividing the LD50 (lethal dose for 50% of the population) by the ED50 (effective dose for 50% of the population). A larger margin of safety indicates a wider gap between the dose that is lethal and the dose that is effective, resulting in a higher level of safety.
Yes, it is possible to overdose on methamphetamine even with a one gram dose. Methamphetamine is a powerful stimulant that affects the central nervous system and can cause a range of serious health effects, including overdose, even with a relatively small amount. It is important to seek immediate medical attention if you suspect a meth overdose.
Coal typically takes millions of years to form. It is created through the transformation of plant material under high pressure and heat over prolonged periods of time.
pot, marajuana. Slang
marajuana
MARAJUANA
Ganja Marajuana
overdoseunderdose
the hemp plant. it has been around for centuries.
Oct 11, 2007
no but marajuana is used in strong painkillers
marajuana speed
Marajuana
Marajuana cocaine missles and turbans
Yes, he is. He was arrested for posetion of marajuana, (or posetion of drugs).