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How you can calculate the maintenance dose in the formulation of controlled release tablets?
Wiki User
∙ 11y ago
Dt = Dose (1 + 0.693 × t/t1/2)
Where,
Dt = Total dose,
Dose = Immediate release dose,
t = Total time period for which sustained release is required,
t1/2 = Half-life of drug.
Wiki User
∙ 11y ago
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