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In absolute refractory period, none of channels are reconfigured, so that second active potential cannot be generated no matter how large the stimulus current is applied to the neuron.

In contrast, in relative refractory period, some but not all of channels are reconfigured, another action potential can be generated but only by a greater stimulus current thatn that originally needed.

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The absolute refractory period is the time during which a neuron cannot generate another action potential, regardless of the strength of the stimulus. The relative refractory period is the time during which a neuron can generate another action potential, but only if the stimulus is stronger than usual.

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Q: Absolute refractory period relative refractory period?
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What is the difference between the effective refractory period and the relative refractory period?

The effective refractory period is the timeframe during which a cardiac cell is completely refractory and cannot respond to any stimulus. The relative refractory period is the period during which a cardiac cell is in a partially recovered state and can only respond to a strong stimulus.


What is relative refactory period?

The relative refractory period is the phase of the cardiac action potential during which a stronger-than-usual stimulus is required to elicit another action potential. It occurs immediately following the absolute refractory period and allows for the heart muscle to be able to respond to a second, stronger stimulus after the initial action potential.


What does the relative refractory period of the T wave represent?

The relative refractory period of the T wave represents a vulnerable period in the cardiac cycle during which a premature beat can trigger an arrhythmia, such as Torsades de Pointes. This period occurs during the repolarization phase, when the myocardium is in a state of partial recovery but not fully refractory.


What causes absolute refractory period?

The absolute refractory period is caused by the inactivation of voltage-gated sodium channels that were opened during the preceding action potential. During this period, the neuron is unable to generate another action potential because these sodium channels are closed and unable to respond to further depolarization. This prevents the neuron from firing multiple action potentials too close together and ensures proper signaling.


What is the channel responsible for absolute refractory period?

The absolute refractory period is primarily controlled by the voltage-gated sodium channels. During this period, these channels are inactivated and unable to open in response to a stimulus, ensuring that an action potential cannot be generated regardless of the strength of the incoming signal.