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What is the ld50 of aspirin?

Updated: 5/23/2024
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Wiki User

15y ago

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It depends on the reason for use:

As a long term anticoagulant or preventative measure for heart disease the standard dose is 81mg per day. This is a baby aspirin dose. This will vary depending on the medical professionals evaluation of the patient. And you should be evaluated first. Research during 2013-2014 showed that daily aspirin may not help all patients and can create harmful effects.

As a painkiller for adults the recommended dose is 1-2 tablets every 4-6 hours which is 275-300mg. Not exceeding 3 doses per day. Do not use if you are on any other anti-coagulants such as Warfarin, or have had a stomach ulcer in the past 12 months. For people who smoke and drink, the chances of stomach bleeding, a rare side effect, is increased.

For Children, it is half that dose MAXIMUM. Do not use to treat symptoms of chicken pox as it may cause a fatal side effect called Reye's syndrome, a rare but possible side effect of Aspirin.

Pregnancy:

Aspirin should NOT TO BE USED DURING PREGNANCY AS HIS MAY CAUSE FETAL DAMAGE, ESPECIALLY IN THE LAST TRIMESTER.

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10y ago
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1mo ago

The LD50 of aspirin is estimated to be between 200-800 mg/kg in humans, meaning that this is the lethal dose that would kill 50% of the test population. It is important to note that aspirin overdose can vary in its effects depending on individual factors such as age, weight, and overall health.

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15y ago

1750 mg/kg 1750 mg/kg

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