ld50 for lamotrigine
192mg/kg in rats. Less immediately available information for humans.
105 mgs per day is the average dose. Sources rxlist.com Drugs.com
dear sir i need complete information about NOEL calculation in cleaning validation
50 years or less, by the dangerous radiation
The LD50/50 (50% mortality in 50 days) for strontium-90 in rats is estimated to be around 2.5 to 3 microcuries per gram of body mass. I do not know if that translates linearly to humans.
the lethal dosis (LD50 = Lethal to 50% of the testet animals) is at 25mg /kg This is mouse-testet
An accurage Lethal Dose for the drug Zopiclone in humans does not seem to be currently available. This information may be useful. History: A 72-year-old hospitalized male died following an intentional overdose of 90 milligrams of zopiclone. The patient was being treated for lung cancer and died approximately 4 to 10 hours after the ingestion (Meatherall, 1997). The authors suggested this may be a minimum lethal dose considering the patient's age, weakened condition and arteriosclerosis. Meatherall RC: Zopiclone fatality in a hospitalized patient. J Forensic Sci. 1997; 42(2):340-3. LD50/LC50 - ANIMAL DATA - ZOPICLONE LD50 - (ORAL) RAT: 827 mg/kg LD50 - (IM) RAT: 295 mg/kg LD50 - (IV) RAT: 280 mg/kg LD50 - (SC) RAT: 540 mg/kg LD50 - (ORAL) MOUSE: 2174 mg/kg LD50 - (IM) MOUSE: 541 mg/kg LD50 - (IV) MOUSE: 321 mg/kg LD50 - (SC) MOUSE: 888 mg/kg Source: RTECS Registry of Toxic Effects of Chemical Substances. National Institute for Occupational Safety and ealth, Cincinnati, O (internet Version). Micromedex Inc., Greenwood Village, CO, 2001. I can tell u that during my drug abuse days I once did 58 7.5 mg pills so 435mg and blackedout. I woke up after I'm not sure how many hours of "sleep" and found i could barely think and standing up was impossible. I'm 21 and 186lbs so it all depends. Worst part about it after the first 8 pills i didnt even realize i was hurting myself or think of the possibilites. Zopiclonse really impairs u i just kept taking more and more
Yes
No.
What are the different mouse techniques?
1530 mg per kilogram bodyweight, when taken orally by a rat (test on humans would be unwise).
The LD50 of chocolate for mice has not yet been determined. It is unlikely that a mouse will kill itself by eating chocolate, as they know when to stop.