The LD50 of phenobarbital in humans is estimated to be around 15 mg/kg when taken orally. LD50 represents the dose at which 50% of the test population would die as a result of the substance.
105 mgs per day is the average dose. Sources rxlist.com Drugs.com
192mg/kg in rats. Less immediately available information for humans.
dear sir i need complete information about NOEL calculation in cleaning validation
50 years or less, by the dangerous radiation
An accurage Lethal Dose for the drug Zopiclone in humans does not seem to be currently available. This information may be useful. History: A 72-year-old hospitalized male died following an intentional overdose of 90 milligrams of zopiclone. The patient was being treated for lung cancer and died approximately 4 to 10 hours after the ingestion (Meatherall, 1997). The authors suggested this may be a minimum lethal dose considering the patient's age, weakened condition and arteriosclerosis. Meatherall RC: Zopiclone fatality in a hospitalized patient. J Forensic Sci. 1997; 42(2):340-3. LD50/LC50 - ANIMAL DATA - ZOPICLONE LD50 - (ORAL) RAT: 827 mg/kg LD50 - (IM) RAT: 295 mg/kg LD50 - (IV) RAT: 280 mg/kg LD50 - (SC) RAT: 540 mg/kg LD50 - (ORAL) MOUSE: 2174 mg/kg LD50 - (IM) MOUSE: 541 mg/kg LD50 - (IV) MOUSE: 321 mg/kg LD50 - (SC) MOUSE: 888 mg/kg Source: RTECS Registry of Toxic Effects of Chemical Substances. National Institute for Occupational Safety and ealth, Cincinnati, O (internet Version). Micromedex Inc., Greenwood Village, CO, 2001. I can tell u that during my drug abuse days I once did 58 7.5 mg pills so 435mg and blackedout. I woke up after I'm not sure how many hours of "sleep" and found i could barely think and standing up was impossible. I'm 21 and 186lbs so it all depends. Worst part about it after the first 8 pills i didnt even realize i was hurting myself or think of the possibilites. Zopiclonse really impairs u i just kept taking more and more
Yes
No.
The LD50 of chocolate for mice has not yet been determined. It is unlikely that a mouse will kill itself by eating chocolate, as they know when to stop.
What are the different mouse techniques?
yes, it take 130ppm standerd for a mouse -- equilivent to 70 cups of coffee for a human ar one sitting
The LD50 (lethal dose for 50% of test subjects) of strontium-90 is not precisely established in humans due to ethical reasons. However, animal studies suggest a range of LD50 values depending on the route of exposure (oral, inhalation, etc.) and health of the animals. Generally, strontium-90 is considered a high-risk radioactive substance with potentially lethal effects at relatively low doses.