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Steroid hormones arelipid-soluble and can dissolve easily into the cell membrane of the target cell to connect with receptors. Protein hormones are water-soluble and connect with receptors at the membrane because it can't diffuse through the membrane.

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15y ago
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1mo ago

Protein hormones are composed of amino acids and generally bind to cell-surface receptors to initiate signaling cascades, while steroid hormones are derived from cholesterol and typically diffuse through cell membranes to bind to receptors in the cytoplasm or nucleus. Protein hormones typically activate second messenger systems, while steroid hormones directly affect gene expression by binding to DNA and regulating transcription.

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Q: What is the difference between protein hormones and steroid hormones and how they communicate with their target cells?
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