Phosphorylase adds the Phosphate group to substrate, but phosphatase takes off the Phosphate group from the substrate. the function of phosphorylase can be considered as same as kinase.
they are all playing key roles in the cellular signalling transduction via control the phosphorylation, the phosphatase can be the negative or positive regulator for different pathways. e.g. PTP1B dephosphorylates the JAK2 to suppress leptin in the hypothalamus that contribute to weight gain.
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Phosphorylase is an enzyme that adds a phosphate group to a molecule, typically to activate it. Phosphatase is an enzyme that removes a phosphate group from a molecule, usually to deactivate it or regulate its activity. Essentially, phosphorylase adds a phosphate group while phosphatase removes a phosphate group.
AMP is an inhibitor of glycogen phosphorylase.
Chloroplasts and mitochondria both contain phosphorylase enzymes because these enzymes are involved in energy metabolism processes that occur in both organelles. Phosphorylase enzymes are responsible for catalyzing the breakdown of glycogen into glucose units in the cytoplasm, releasing energy in the form of ATP which is essential for cellular energy production.
When prostate cancer spreads to other parts of the body, such as the bones, the acid phosphatase levels may increase. Acid phosphatase is an enzyme that can be elevated in cases of bone metastasis from prostate cancer, as it is released by prostate cancer cells in the bones. Monitoring acid phosphatase levels can help in assessing the extent of metastasis and response to treatment.
No. Insulin converts glucose into glycogen for storage in the body. Glucagon converts glycogen into glucose. (it's the various cells in the body that do the conversion in either case, insulin and glucagon are hormones that induce the shift in the metabolism.)
Starch phosphorylase is important in metabolism as it helps break down starch into glucose units for energy production. This enzyme plays a key role in glycogen degradation in animals and starch degradation in plants, providing essential substrates for energy metabolism. Additionally, starch phosphorylase helps regulate blood glucose levels and is involved in various cellular processes related to energy balance.