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Properties Endotoxin Exotoxin

Chemical nature Lipopolysaccharide protein

Mol Weight 10 kDa 50-1000 kDa

Relationship to cell Part of outer membrane Extracellular

Heat effect Not denatured Denatured

Can be toxoided No Yes

Specificity Low High

Pyrogenicity Yes Occasional

Produced by G-ve bacteria G+ve bacteria

Antigenicity Poor Good

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Related Questions

Is whooping cough endotoxin?

no it is exotoxin , as its a gram positve baceria


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What does the toxin Endotoxin do?

The amount of endotoxin in protein, peptide or antibody samples is measured by the Limulus Amebocyte Lysate (LAL) test with an endotoxin kit. The concentration of endotoxin in the test specimens is calculated by the LAL kit by chromogenic signal in the presence of endotoxin. This measurement is performed on a microplagin absorption reader at 405 nm. Protein and antibody samples are measured every 30 minutes. The importance of determining the level of endotoxin in evaluating the effectiveness of endotoxin removal methods as well as preventing endotoxic shocks and animals injected with endotoxin-contaminated proteins is very important.


Is endotoxin an exogenous pyrogen?

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What exotoxin is produced from phage?

Exotoxin produced from a bacteriophage is called diphtheria toxin. It is produced by certain strains of Corynebacterium diphtheriae bacteria when infected by a specific bacteriophage carrying the gene for the toxin.


Is an endotoxin an A-B toxin?

The term "endotoxin" is a bit wonky. Originally, it was intended solely to mean a toxin(s) not secreted by the bacterium cell until after cell death. Since then, however, the term has come to refer to the cell wall components of Gram-negative bacteria, most specifically lipopolysaccharide (LPS). In the case of the term "endotoxin" referring to LPS, then, no -- LPS is a sole toxin (an "A"). However, when the more general meaning of the term "endotoxin" is used, the toxin released may be an A-B toxin.


Which bacteria produces an exotoxin causing toxic shock syndrome?

Staphylococcus aureus is the bacterium that produces an exotoxin (specifically, TSST-1 toxin) responsible for causing toxic shock syndrome.


What is endogenous endotoxin?

Endogenous endotoxin refers to lipopolysaccharides (LPS) that are produced by the body's own cells, particularly gut bacteria. These endotoxins can trigger an immune response and contribute to inflammation and other health issues when released into the bloodstream.


What can Endotoxin in sterile injectable drugs cause?

Endotoxin in sterile injectable drugs can cause severe systemic inflammatory response known as endotoxemia, resulting in symptoms such as fever, chills, hypotension, and potentially fatal outcomes like septic shock. Therefore, it is crucial to ensure strict quality control measures to prevent endotoxin contamination in sterile injectable drugs.


Does bortella pertussis produce exotoxin?

Yes, Bordetella pertussis produces an exotoxin called pertussis toxin. This toxin plays a key role in the pathogenesis of whooping cough by interfering with the host's immune response and contributing to the characteristic symptoms of the disease.


What is difference between as on and as at?

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