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Endotoxin in sterile injectable drugs can cause severe systemic inflammatory response known as endotoxemia, resulting in symptoms such as fever, chills, hypotension, and potentially fatal outcomes like septic shock. Therefore, it is crucial to ensure strict quality control measures to prevent endotoxin contamination in sterile injectable drugs.

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Q: What can Endotoxin in sterile injectable drugs cause?
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Injectable drugs are tested for endotoxins by?

performing a Limulus Amebocyte Lysate (LAL) test, which detects the presence of endotoxins in the drug product. This test involves lysing amebocyte cells found in the blood of horseshoe crabs, which then interact with endotoxins to produce a gel clot formation, indicating the presence of endotoxins. The LAL test is a sensitive and specific method for ensuring that injectable drugs are free from harmful endotoxins that could cause adverse reactions in patients.


Drugs change the chemical processes in what organ to cause addiction?

Brain


Can drugs cause color blindness?

Yes, certain drugs have been known to cause temporary or permanent color vision disturbances, including color blindness. This can occur as a side effect of medication, such as specific antibiotics, antimalarial drugs, or certain medications used in cancer treatments. If you have concerns about your color vision while taking medication, it is important to consult with a healthcare provider.


What non vesicant?

Some examples of non-vesicant chemotherapeutic drugs include paclitaxel, carboplatin, and doxorubicin. These drugs are less likely to cause tissue damage if they leak out of the vein during administration compared to vesicants.


What medications may cause gastrointestinal bleeding?

Medications that may cause gastrointestinal bleeding include nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen, anticoagulants like warfarin, corticosteroids, and certain antidepressants like SSRIs. It is important to always read the label and consult with a healthcare provider if you have concerns.