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RossHemophilia is most often caused by mutations in the F8 gene, located on the X chromosome. This gene provides instructions for making a protein called factor VIII, which is essential for blood clotting. Mutations in the F8 gene can result in reduced or absent levels of factor VIII, leading to the characteristic bleeding problems seen in hemophilia.
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What is Inherited on a sex chromosome that can cause human genetic disorder such as color blindness and hemphilia?
Inherited on a sex chromosome, genetic disorders such as color blindness and hemophilia are caused by mutations in specific genes located on the X chromosome. These disorders are more commonly seen in males because they have only one X chromosome, making them more likely to express recessive X-linked traits. Females, with two X chromosomes, are typically carriers of the mutated gene but may not exhibit the disorder unless they inherit two copies of the mutated gene.
Why is hemophilia rarely expressed in females?
Hemophilia is a genetic disorder that is X-linked, meaning it is carried on the X chromosome. Females have two X chromosomes, so even if one carries the gene for hemophilia, the other X chromosome can usually compensate for it. In males, who only have one X chromosome, the gene for hemophilia is more likely to be expressed.
What kind of gene pair is found in the female carrier of a sex linked disorder?
In the female carrier of a sex-linked disorder, there would typically be one normal allele and one mutated allele for the gene associated with the disorder on the X chromosome. This is because females have two X chromosomes, and one copy of the X chromosome with the mutated allele can be masked by the normal allele on the other X chromosome.
Do Male hemophiliacs inherit the disease from their?
Yes, males inherit hemophilia from their mothers who carry the gene on their X chromosome. Hemophilia is a genetic disorder that primarily affects males because they have only one X chromosome.
Does hemophilia result from too many or too few chromosomes?
The gene for the most well known form of hemophilia is located on the X chromosome. It is not the result of too many or too few chromosomes. A male receives only one X chromosome while the receives two X chromosomes. These gene codes for factor VIII, one of the factors within the clotting cascade. If a female inherits the mutated gene, she has a second gene on the other X chromosome. However, she is capable of passing the gene for hemophilia onto her children. Males inherit one X chromosome and so have hemophilia. This is for informational purposes only and should not be construed as a complete answer.
