An action potential in the neuron
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When an action potential reaches the axon terminal, it triggers the opening of voltage-gated calcium channels. The influx of calcium causes the synaptic vesicles to move towards the cell membrane and fuse with it, releasing neurotransmitters into the synaptic cleft.
Calcium ions are responsible for triggering the fusion of neurotransmitter vesicles with the axon's membrane during the conduction of a nerve impulse. The influx of calcium ions into the neuron's terminal triggers the release of neurotransmitters into the synaptic cleft.
The axon terminals of a neuron form the presynaptic neuronal membrane. These structures contain synaptic vesicles that store neurotransmitters for release at the synapse.
The bubbles contain neurotransmitters that transmit signals between neurons. When they cross the synapse, they bind to receptors on the receiving neuron, triggering a response that propagates the signal along the neuron.
Neurotransmitters are synthesized inside the neuron's cell body and stored in vesicles at the nerve terminal. When an action potential occurs, the neurotransmitters are released into the synaptic cleft to transmit signals to the next neuron.
When a neuron is resting, the inside of the cell membrane is more negative compared to the outside due to the unequal distribution of ions. This difference in charge is maintained by the sodium-potassium pump, which actively transports ions across the membrane to establish the resting membrane potential.