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due to lack of b12
No HCl and intrinsic factor = pernicious anemia
Wiki User
∙ 12y ago
Inadequate intrinsic factor is associated with vitamin B12 deficiency, as intrinsic factor is necessary for the absorption of this essential nutrient in the gut. Vitamin B12 deficiency can lead to symptoms such as anemia, fatigue, and neurological problems. It is commonly seen in individuals with pernicious anemia or autoimmune conditions affecting the stomach lining.
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Aids in absorption of vitamin b12?
Intrinsic factor, a protein produced in the stomach, helps in the absorption of vitamin B12. This vitamin is crucial for red blood cell formation and neurological function. Absorption of vitamin B12 occurs in the small intestine, where it binds to intrinsic factor for transport into the bloodstream.
A protein secreted by the stomach that is necessary for the absorption of vitamin B12?
The protein secreted by the stomach that is necessary for the absorption of vitamin B12 is called intrinsic factor. Intrinsic factor binds to vitamin B12 in the small intestine, allowing for its absorption into the bloodstream. Without intrinsic factor, vitamin B12 cannot be effectively absorbed and can lead to a deficiency.
Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?
Oral administration of vitamin B12 is not effective for pernicious anemia because the condition involves a lack of intrinsic factor, which is needed for the absorption of B12 in the intestines. Without intrinsic factor, the intestines are unable to absorb enough B12 from oral supplements to treat the deficiency. In such cases, B12 injections are typically used for effective treatment.
Which pathway of blood coagulation has factor VIII th as important factor?
Factor VIII is crucial in the intrinsic pathway of the blood coagulation system. It helps in the activation of factor X, which is a key step in the formation of a blood clot. Without factor VIII, this pathway would be impaired, leading to difficulties in clot formation.
What is the rate and extent to which a vitamin is absorbed and used in the body is known as?
intrinsic factor
What the importance of intrinsic factor?
Intrinsic factor is glycoprotein that is produced by the parietal cells of the stomach.
Why do you need intrinsic factor?
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
Aids in absorption of vitamin b12?
Intrinsic factor, a protein produced in the stomach, helps in the absorption of vitamin B12. This vitamin is crucial for red blood cell formation and neurological function. Absorption of vitamin B12 occurs in the small intestine, where it binds to intrinsic factor for transport into the bloodstream.
Which cells produce intrinsic factor?
Intrinsic factor is produced in the fundus and body of the stomach by parietal cells that line the stomach. The purpose of intrinsic factor is so vitamin B can be absorbed in the small intestine.
Which blood component is associated with Von Willenbrand disease?
von Willebrand disease results from inadequate von Willebrand factor. This problem is a blood clotting disorder.
What problems are associated with an inadequate diet?
many
What foods increase intrinsic factor?
what foods help increase intrisic factor
Where does the absorption of vitamin B12 occur?
The vitamin B12 is a very important nutrient; it lowers risk of stroke, heart disease, cancer, Parkinson's, and Alzheimer's disease. The vitamin begins to absorb in the mouth, in contrast to most nutrients.
Which nutrient requires intrinsic factor for absorption?
Vitamin B12 requires intrinsic factor for absorption in the small intestine. Intrinsic factor is produced by the stomach and binds to vitamin B12 to facilitate its absorption in the ileum. Without intrinsic factor, vitamin B12 absorption is impaired, leading to deficiency.
What is the function of the intrinsic factor?
Intrinsic factor is necessary for the proper absorption of vitamin b12 which is necessary for red blood cell maturation, and therefore prevents pernicious anemia
How does one increase production of intrinsic factor?
what foods help increase intrisic factor
Is hydrochloric acid necessary to produce the intrinsic factor for cobalamin?
No, hydrochloric acid (HCl) is not necessary to produce the intrinsic factor for cobalamin. HCl is needed along with gastric enzymes to free Cobalamin (B12) from its polypeptide linkages in food. The intrinsic factor involved with the digestion and absorption of Cobalamin (B12) is a glycoprotein.
