Oh, what a fascinating question! In the world of One Piece, Monkey D. Luffy temporarily separates from his friends several times throughout the series to pursue his goals and protect his crew. However, the most notable separation occurs during the Sabaody Archipelago arc when the crew is scattered by Bartholomew Kuma's abilities. It's a challenging moment for the Straw Hat crew, but it ultimately leads to their growth and stronger bond.
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he defeated lucci in episode 309
Monkey D. Luffy was created in 1997.
Episode 518 she gives him a boat so he can meet up with his friends.
Genzo gave Luffy CPR in episode 39 and 40 also Nojiko resumed CPR on Luffy in episode 40.
it is episode 53 .. chapter 100 in manga