Your first cousin's daughter is first cousin once removed to your grandson, and he to her.
Your second cousin's daughter is second cousin once removed to your grandson, and he to her.
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Your son and your sisters child are first cousins. The granddaughter is out of synch by a generation. That will make them first cousins once removed.
If you really need a relationship term, use granddaughter-in-law. Most people would merely say "my grandson's wife."
Your grandfather's brother's granddaughter is your second cousin.
The Czarina at the time of the Russian Revalution was Alexadra. Alexandra was the granddaughter of Queen Victoria. Because of this relationship at the time of the Revolution she had cousins on the throne of Germany, Romania, Spain, England, Norway and Greece.
Yes, they are related. While it is a distant relationship, you are cousins.