The laws of gravity as expressed by Sir Issac Newton were determined before Dr. Louis Pasteur discovered penicillin.
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Alexander Flemming first discovered, cultured and used penicillin
thousands of years before Columbus discovered America (go to answers.com)
When an apple hit his head and he discovered gravity! It certainly knocked some sense into him.
Isaac Newton was 44 years old when the Law of gravity was published in the book Principia.
Guns were invented by humans, so no one discovered it. Discovery is when a person learns something about nature without the influence of humans. For example, we discovered friction, gravity, reflection, etc. just by feeling, seeing, etc., and not by inventing. Sir Isaac Newton noticed gravity when an apple fell from a tree. You can witness friction by rubbing your hands. None of these two actions directly require inventions.