Your ancestors can be Jewish if they were Jewish. Whether the surname of your mother seems to be associated with Jews or not does not change that.
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It was Susan Mosee. Annie Oakley's mother's maiden name was Wise.
In Jewish law you are Jewish if your mother is Jewish. So long as you know that your mother and her mother (and her mother, etc.) isn't Jewish then you are not Jewish. There is no magical (or medical or any scientific way) to know if you're Jewish.
Gretchen Ludwig was her mothers maiden name
No his mother was a German. NOT JEWISH.
Any surname can be a mother's maiden name. A maiden name is merely the surname a woman uses (typically her father's, given to her at birth) before she marries and takes her husband's surname if she chooses to do so.