Why cefotaxime doesn't given orally?

Answer 1

Because of the effectiveness of the blood-brain barrier in preventing the passage of substances into the brain, medications must be delivered directly into the patient's veins (intravenously, or by IV), at very high doses.

Answer 2

The drug is intended to be given to the patient either in an intramuscular injection - or by intravenous infusion. Used orally - it can cause problems in patients that have impaired liver functionality.

Answer 3

By the time the antibiotic gets into the stomach it has lost the full strength of the medicine.