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simple answer.....never, if you're thinking naltrexone will get you high. If you mean "how long after you take the tablet, can you use an opioid and get the desired effect?" Then in that case, the naltrexone is in your system for 3 days, so on the 4th day on not taking naltrexone, you will get the effect from any opioid. I'm takin them ATM, but have only just started and am only taking half a tab per day, but I'm having bad side effects, so am trying to find out if by taking half, does that mean it's in my system for 1.5day (as a full tab lasts 3 days), but even my keyworkers don't know :(

Hope that helps.

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13y ago

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Q: When can you get hi off of naltrexone?
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