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High Dose Hook Effect refers to measured levels of antigen displaying a significantly lower absorbance than the actual level present in a sample. This appears when a simultaneous ELISA assay is saturated by a very high concentration of sample antigen binding to all available sites on both the solid phase antibody as well as the detection antibody and thereby preventing the sandwich-formation. The antigen-saturated detection antibodies in solution will be washed off giving a falsely low signal. A "hook" is observed in the curve when data is plotted as a signal versus antigen concentration.
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What is the Prozone hook effect?
Prozone effect or (high-dose) hook effect is the cause of a false negative or false low result which occur from an excess amount of antigen or antibody in a sample due to the inability of an analyte to bind to a receptor site.
What effect does high-level-control fluoroscopy have on radiation dose?
High-level-control fluoroscopy increases radiation dose to the patient.
What is the lethal airborne dose of an Ebola virus?
There is NO "no effect dose" dose or "lethal effect" dose for viruses, bacteria, and other microorganisms, because they make you ill by multiplying at first in number ('growth')
How high should you hang a clothes hook?
A person should a clothes hook high enough so they can reach it. The hook should also be high enough so the clothes will not reach the floor.
How does shape of sail effect sailboat speed?
the shape dose effect it.
What effect dose gravity have on motion?
hbuyf
Does heredity affect flexibility?
it dose not effect it
What is a moderate dose effect of marijuana?
sleepenisses
What is dose effect?
yes it dose effect the glowworms because you breath in oxygen and let out carbon dioxide wich makes it hard for the glowworms to breath... =]
What is pharmacological dose?
A pharmacological dose is the amount of a drug that treats illness effectively. It is the smallest dose needed to provide the wanted effect.
How can demineralization be prevented?
With a prescription of high-dose fluoride gel. Ask your dentist what high-dose fluoride gel is.
Who created the high dose flu shot?
The manufacturer of the high dose flu vaccine that is approved for use in the US is Sanofi Pasteur, Inc. They make the Fluzone High-Dose formulation of influenza vaccine.
