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Chronic microangiopapthic disease is when you have problems with tiny blood vessels. This disease is common with age the tiny vessels get stiff, crackly and sometimes they get blocked. Which can cause the vessel not to get enough blood and some of the white matter gets damaged and leads to a brain shrinkage.
Chronic microvascular ischemic changes are when there are tiny blood vessels in the brain that have ruptured or clotted. This causes very small strokes.