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When you believe you're ready. Never, if you want to keep all of your brain cells. When you believe you're ready... Yes. Leave it at that though, theres no proof what so ever that ecstasy costs you any permanent brain damage. In fact the only effect it has on the brain is the temporary lowering of your seratonin levels, which will return 100% to normal after 2-3 weeks of abstinence.
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