The most important natural body anticoagulant is heparin. Heparin is usually administered by injection to prevent the blood from clotting.
Heparin is the body's natural anticoagulant.
I can partly answer this question: Basophils, which are granular leukocytes, are a part of our bodies natural makeup, they produce heparin (an anticoagulant), histimines (an inflammatory substance), and serotonin (a vasoconstictor).
Much of the histamine in the body is produced by the granules in mast cells and basophils as part of a local immune response to the presence of invading bodies.
When histamine is produced in the body, it can be over-produced because we are taking too much of one thing or another that our body cannot use.
Diet is a very important consideration because the amount of vitamin K in the body affects how anticoagulant drugs work.
Histamine is found in the granules of mast cells where it is bound with an acidic protein and heparin(positively charged) while histamine itself is negatively charged.
histamine is a compound produced in the body which causes pain and sweeling
Coumadin is an anticoagulant (blood thinner). It prevents clots from forming.
They have completely different functions in the body; histamine stimulates certain kinds of immune responses, and serotonin is a neuro-transmitter.