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The core substance of the wine is alcohol, alcohol liver, detoxification and excretion by decomposition. Large amounts of alcohol on the brain has inhibitory effect on hepatic toxic, may cause alcoholic liver disease. If the patient has a longer drinking history, symptoms are relatively slow, such as the liver area discomfort or even pain, further can lead to alcoholic hepatitis. In addition to the above symptoms, also manifested nausea, anorexia, fatigue, weight loss, serious person can appear icteric, even liver failure. Normal average daily alcohol 80 grams of alcohol, 8 years appeared in alcoholic liver cirrhosis.

In general, when the body alcohol concentration reaches 0.05% - 0.2%, the human brain inhibitory function weakened, loss of memory, judgment, understanding decreased obviously.

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