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Diuretics (For e.g. Thiazide) causes Hypokalemia. It will cause the potassium to be secreted in urine. Due to hypokalemia, there will be less insulin release (as both depend on each other). The less amount of insulin release cause the glucose level to rise in plasma, causing Hyperglycemia. As the glucose level rises, there will be more Triglycerides form, it will lead to LDL(low density lipoproteins) and Very Low Density Liporoteins- These are bad cholestrol-Causing Hyperlipidemia.

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Q: How do diuretics cause hyperlipidemia?
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