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Absorption:
the amount of drug reaches the systemic circulation is called absorption.
Distribution:
the drug reversibly leaves the blood stream and enters into interstitial space or tissues.
Elimination:
irreversible removal of drug from body by excretion or metabolism of drug
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What are the five basic stages of pharmacokinetics?
The five basic stages of pharmacokinetics are absorption, distribution, metabolism, excretion, and elimination. Absorption refers to the movement of a drug into the bloodstream, distribution is the spread of the drug throughout the body, metabolism involves the conversion of the drug into metabolites, excretion is the removal of the drug or its metabolites from the body, and elimination is the combination of metabolism and excretion.
What are the four stages of pharmokinetics?
The four stages of pharmacokinetics are absorption (movement of drug into bloodstream), distribution (spread of drug throughout body), metabolism (breakdown of drug into metabolites), and elimination (removal of drug or metabolites from the body).
What does tmax stand for?
time when drug is fully available at the max (when the absorption rate and elimination rate of the drug equals)
Is the esophagus digestion absorption or elimination?
absorption
Metabolism and absorption of amoxicillin drug?
§ Absorption: fully dissociated in aqueous solution at physiological pH. The components are rapidly and well absorbed by the oral route of administration. Absorption of Augmentin is optimized when taken at the start of a meal. § Distribution: Both clavulanate and amoxicillin have low levels of serum binding; about 70% remains free in the serum. § Metabolism: Elimination: All of these data indicate that the elimination pharmacokinetics seen in adults also apply to children with mature kidney function.
Process that brings a drug from the administration site into the blood stream is called?
The process that brings a drug from the administration site into the bloodstream is called absorption. It refers to the movement of a drug from its site of administration into the bloodstream for distribution throughout the body. Factors such as route of administration, drug formulation, and physiological properties can affect drug absorption.
What is the pharmacodynamic phase of drug action?
Pharmacokinetics refer to how the drug works through its mechanisms and how the drug interacts with the body. Absorption, distribution, metabolism, excretion and elimination of the drug from the body are all part of the pharmacokinetic phase of a drug trial. Pharmacists and industrial scientists are the foremost experts in this field. In a hospital or health clinic, pharmacists are involved in dosing drugs based on its pharmacokinetic profile in a patient - such as in babies and pediatric patients.
What factors determine a drug's rate of metabolism?
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties.
What are the three phases of drug effects?
Pharmacokinetic phase: involves the absorption, distribution, metabolism, and elimination of the drug in the body. Pharmacodynamic phase: refers to the drug's interaction with its target receptors and the subsequent biochemical and physiological effects. Phase of termination: marks the decline of drug effects as the body clears the drug through metabolism and excretion.
What are the functions of the intestines?
Digestion, absorption, and elimination.
What is effect of pH on absorption of a drug?
the more ionized the drug is the less absorption
What is Terminal half life?
Terminal half-life is the time it takes for the concentration of a drug in the body to decrease by half during the elimination phase, after reaching steady state. It is used to estimate how long a drug will stay in the body once the dosing is stopped. Terminal half-life is influenced by factors such as drug metabolism and elimination rate.
