No, an enema is beneficial if administered carefully and correctly. It is best to read info from the many sites on the internet. The basics are to use water that is pure and be sure to add a teaspoon of salt for every 1000ml of water to make it less irritating and cause less absorption.
Yes, they can be. You can lose water and normal electrolytes cause an imbalance in the body. They are only used for the correct reason not for recreation.
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An enema would hurt if you inserted the tip into the rectum improperly or too quickly. A little cramping may occur in the lower half of the abdomen but it the process shouldn't be too painful.
No, in most cases an enema would not hurt if performed correctly. There can be some feelings of pressure in the stomach area but there should be no pain.