GLaDOS is different in Portal 2 because she is in another body. We know there are multiple GLaDOS chassis because in the comic there are multiple GLaDOS prototypes and in the games she activates multiple cores, is put in to the POTaTOS body and tells the robots P-Body and ATLAS that there is an intruder in one of her old chassis and forces them to confront it. However her new body is and old prototype and has very limited power over the facility and in the multiplayer function the robots put discs into the GLaDOS mainframe and restore her to full power. The way the prototype body got down to the GLaDOS control room is decaying walls and floors that crumble over the decades allowing the body to drop in.
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In Portal(2) GLaDOS stands for the Genetic Lifeform and Disk Operating System.
In Portal 2, GLaDOS looks different due to the changes made to her appearance by the game developers. The redesign was intended to reflect her evolution throughout the game's storyline, as she undergoes various transformations and upgrades. The changes in her appearance also serve to visually represent her deteriorating state and shifting motivations as the narrative progresses.
GLaDOS Genetic Lifeform and Disk Operating System I'd say her real name but it would ruin the surprise.
In Portal 1 people say that Caroline hasn't had her mind put in but she kills everyone in the facility (Aperture Laboratories) so it is not that. So can you figure it out?
In Portal 2 GLaDOS says something in fast motion to "explain" how to solve the test. What she is really doing is quoting a line from Moby Dick: "...and methodically knocking people's hats off--then I account it high time to get to sea as soon as I can." Now you really can remember what she said in slow motion like she told you to!