He pops up out of no where and tells you news about N then leaves.
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looker only comes when you beat the game and he gives you a Super Rod and you meet him when you find the seven sages.
He says he is going to a distant place to look for a legendary pokemon, but he doesn't give you anything.
After you have Looker arrest the last sage out of the Seven Sages, He should thank you and he should also tell about a boy who sounds exactly like N, who has been seen with a dragon pokemon somewhere far away... ^_^
I'm not very sure about this but search for a boat to see if you can find looker and talk to lots of people in the game cause they might give you hints like legendary locations and where you could find a person important in the game like bianca or the champion who knows the game is full of mysterious?
If you mean after you find the other sages . well you cant find him ever again you will have to wait for the sequel of pokemon black and white so really you cant find N or Ghetsis ever again in your currant pokemon game