Nero from Devil May Cry 4, from the top of my head.
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Your question is too broad for anyone to answer it with certainty. I suggest narrowing your question, by giving the title of the video game.
Blue Mars - video game - happened in 2009.
Mouse wields Pattimo who is a talking guitar that sheaths a sword in the PS2 game "Ephemeral Fantasia".
A video game character made by SEGA.
lenin