There is no canon last name for Drew. Nor is there a canon last name for May.
Most of the fan base uses Hayden like they use Maple for May. Some use his Japanese name Shuu as a last name. There are many people who don't use any of these but something they made up.
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Iris Cuasorome is a character in Pokemon.
Ash's last name is Ketchum in Pokémon.
In the Pokemon anime, the only two characters to have last names are Ash Ketchum and Tracey Sketchit, so Dawn really has no last name. However, in many Pokemon Fan Fictions her last name is commonly referred to as Berlitz.
Serena's last name has not been mentioned in the Anime, game, or on any Pokemon wiki.
It's Paul Allen